Bioinspired Techniques in Freeze Casting: A Survey of Processes, Current Advances, and Future Directions

Abstract

Freeze casting, popularly known as ice templating or freeze gelation, is a mechanical method to fabricate scaffolds of desirable properties and materials. Aerospace engineering, the healthcare sector, manufacturing department, and automotive industries are the different fields where freeze casting has been used. Bioinspiration refers to the translation of biological systems into new and innovative creations. Bioinspired materials are extensively used in freeze casting methods such as ceramide, spines of porcupine fish, and collagen. Due to the tunable properties and production of complex structures with ease, biomaterials have found numerous applications in the ice templating method. This review rigorously explains the freeze casting process and the effect of thermal conductivity, stress, and electrostatic repulsion on the porous materials. Also, we have discussed the different biomaterial polymers used in freeze casting along with different methods involved.

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“…400,401,675,677,680–682 The structural parameters such as the morphology, thickness and porosity of the structures can be adjusted by controlling the freezing process (temperature gradient 54 and cooling rate 683 ), morphology, 684 concentration 685 of building blocks, and additive type and solvent. 686…”