Biokinetische Normwerte bei der intravenösen Glucosebelastung

Dost, F. H.; Gladtke, E; Hattingberg, M. v.; Rind, H

doi:10.1007/bf01810793

Cited by 9 publications

(2 citation statements)

References 5 publications

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“…The newborn infant is subject to a variety of metabolie and hormonal reactions not found during later periods of life (Comblath, Parker, Reisner, Forbes and DaugluuJay 1965, Euler, Larsson and Persson 1964, Dost, Gladtke, Hattingberg and Rind 1968, Westpha/ 1968. In response to glucose infusion, a newbom infant increases blood growth hormone (GH) level (Comblath et al 1965, Westphal 1968 whereas children and adults react with decrease.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Stress on Growth Hormone, Glucose and Glycerol Levels in Newborn Infants

Stubbe¹,

Wolf²

1971

Horm Metab Res

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This study was performed to evaluate the influence of stress on growth hormone, glycerol and glucose levels in the blood in different age groups of full-term, newborn infants. Growth hormone decreased whereas glycerol and blood glucose increased after aseries of heel-pricks. Since glycerol und glucose changes may weil be explained by catecholamine release, the failure of the newborn infant to increase growth hormone concentration as do individuals during Iater life is evidence that adaptation of metabolic and hormonal reactions occurs during the postnatal period.

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Section: Introductionmentioning

confidence: 99%

The Effect of Stress on Growth Hormone, Glucose and Glycerol Levels in Newborn Infants

Stubbe¹,

Wolf²

1971

Horm Metab Res

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“…There is no protein binding after entering the intravascular space. It can also be assumed, that the distribution between the intravascular and extravascular spaces occurs similar to other monosaccharides [25], with adequate speed. The Bateman-function, which describes the D-xylose concentration in blood with good approximation, contains two exponential functions whose exponents kl and k2 can be defined as the rate constant of invasion (k0 and the rate constant of elimination (k:) [21].…”

Section: Resultsmentioning

confidence: 99%

The age-dependence of intestinal absorption using d-xylose as an example

1977

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In 40 infants the serum concentrations of D-xylose were measured from capillary blood samples up to 300 min after an oral dosage of 0.5 g of D-xylose per kg body weight. The parameters of the absorption kinetics, which are calculated by a digital computer program, showed an age-dependent behavior. Infants up to the age of 2 months have lower maximal serum concentrations compared to older ones because of a larger volume of distribution. The rate constant of invasion k1, which serves as a measure for the rate of intestinal absorption and the rate constant of elimination k2 were significantly lower in infants up to the age of 2 months compared to older ones. The quotient of k1:k2 was independent of age. The time it took to reach maximal serum concentration was significantly longer in young infants. By adding metoclopramide simultanously to the oral D-xylose doses it could be demonstrated that the slower motility of the gastrointestinal tract in newborns and young infants is not exclusively responsible for the slower rate of absorption of D-xylose. Comparing the absorption rates in 26 infants after different D-xylose dosages a saturation kinetics may be supposed.

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Biguanide (Experimenteller Teil)

Beckmann¹

1971

Oral Wirksame Antidiabetika

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Biokinetische Normwerte bei der intravenösen Glucosebelastung

Cited by 9 publications

References 5 publications

The Effect of Stress on Growth Hormone, Glucose and Glycerol Levels in Newborn Infants

The Effect of Stress on Growth Hormone, Glucose and Glycerol Levels in Newborn Infants

The age-dependence of intestinal absorption using d-xylose as an example

Biguanide (Experimenteller Teil)

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