Biologic Agents to Enhance Fracture Healing

Markel, Mark D.; Seeherman, Howard

doi:10.1002/9781119108757.ch12

Cited by 1 publication

(1 citation statement)

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“…Inclsuion Criteria: Patients of either gender between the ages of eighteen (18) and sixty (60) years who had closed femoral diaphysial fractures with delayed or non-union, were inlcuded.…”

Section: Methodsmentioning

confidence: 99%

Role of Percutaneous Bone Marrow Aspirate in the Management of Femoral Delayed Union and Non Union Fractures

Muhammad Rehan Saleem,

Rana Shahbaz Ahmad,

Shahzad Inam

et al. 2023

PAFMJ

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Objective: The objective of the study is to radiologically ascertain bone union following percutaneous autologous bone marrow aspirate injection in the management of delayed union and non-union fractures of femur. Study design: Case series. Duration and place of Study: Department of Orthopedics, Combined Military Hospital, Rawalpindi Pakistan, from Jan to Jun 2019. Methodology: Forty-two (42) patients of fracture femur who fulfilled the inclusion criteria were enrolled in the study. Fresh radiographs of affected side were performed to document cases of delayed union and nonunion. 50ml of bone marrow aspirate from iliac crest was injected at fracture site. Results were evaluated after 12 weeks with the help of radiographs to see radiological union of bone. Results: A total of 42 patients were included in the study. 37(88.09%) were males and 5(11.9%) were females between the ages of 18 and 60 years. The mean age of patients was calculated to be 34.80±11.17 years. Radiological union was achieved in 32(76.19%) patients. Conclusion: Radiological assessment shows percutaneous injection of bone marrow as a safe procedure with bone healing in 12 weeks in patients with non-union or delayed union.

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“…Inclsuion Criteria: Patients of either gender between the ages of eighteen (18) and sixty (60) years who had closed femoral diaphysial fractures with delayed or non-union, were inlcuded.…”

Section: Methodsmentioning

confidence: 99%