2004
DOI: 10.1002/msc.56
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Biologic agents used to treat rheumatoid arthritis and their relevance to podiatrists: a practice update

Abstract: This review considers the pharmacological management of rheumatoid arthritis including the role of anti-tumour necrosis factor alpha (TNFalpha) agents, as a precursor to highlighting some of the issues for podiatrists involved in the care of patients on this particular medication.

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Cited by 10 publications
(11 citation statements)
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“…Pharmacological management of RA has additional consequences for foot health, with medications being associated with increased risk of infection [10, 11]. The sequelae of this spectrum of foot pathology are loss of function, reductions in mobility, quality of life and social participation [12] and a potential negative impact on self- image [13].…”
Section: Introductionmentioning
confidence: 99%
“…Pharmacological management of RA has additional consequences for foot health, with medications being associated with increased risk of infection [10, 11]. The sequelae of this spectrum of foot pathology are loss of function, reductions in mobility, quality of life and social participation [12] and a potential negative impact on self- image [13].…”
Section: Introductionmentioning
confidence: 99%
“…The structural and functional changes in the feet often affect gait and mobility (Turner et al, ; Woodburn et al, ; Turner et al, ), impacting negatively on the patient's quality of life (Otter et al, ; Wickman et al, ) and specifically restricting the choice of footwear (Goodacre and Candy, ; Williams et al, , ). For some people with RA, the structural changes are a factor in foot ulcer development (Firth et al, ), with the risk of infection, particularly if the patient's medical management includes the use of immunosuppressive drugs (Otter et al, ; Wilske, ).…”
Section: Introductionmentioning
confidence: 99%
“…Seventy-five percent (75%) of patients with RA report foot pain within four years of diagnosis, with the degree of disability progressing with the course of the disease [4]. Shi stated that virtually 100% of patients report foot problems within 10 years of disease onset [5].…”
Section: Introductionmentioning
confidence: 99%