Summary. The method of treating endodontically infected teeth with periapical involvement, by pushing Spad paste beyond the apex, was evaluated both radiographically and histologically 3 months aftr treatment. Sixteen root canals in a dog were used, on which periapical lesions had been experimentally instrumented and filled with Spad paste and gutta‐percha points, after the root canal filling paste had been extruded periapically. The radiographic investigation did not show any evidence of periapical tissur repair or significant absorption of the extruded paste. The most profound histological finding was necrosis of the alvolar bone. Inflammation or extensive necrosos of the apical periodontal ligament, resorption of the teeth and ankylosis were also observed. The rusults of this experiment do not support the use of this method of treatment with Spad.