2018
DOI: 10.1016/j.ijrobp.2018.07.1652
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Biologic Subtypes of Primary Breast Tumors Exhibit Differences in the Radiosensitivity Index

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“…RSI may differ according to breast cancer subtype. Differences in breast tumor biology which are recognized to carry ramifications for systemic therapy treatment selection may similarly be useful for selection of patients needing intensified radiation treatment strategies [52].…”
Section: Tools Specifically Designed For Local-regional Recurrence and Benefit From Radiation Therapymentioning
confidence: 99%
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“…RSI may differ according to breast cancer subtype. Differences in breast tumor biology which are recognized to carry ramifications for systemic therapy treatment selection may similarly be useful for selection of patients needing intensified radiation treatment strategies [52].…”
Section: Tools Specifically Designed For Local-regional Recurrence and Benefit From Radiation Therapymentioning
confidence: 99%
“…Differences in breast tumor biology which are recognized to carry ramifications for systemic therapy treatment selection may similarly be useful for selection of patients needing intensified radiation treatment strategies. 51 Integration of RSI with molecular subtype showed that radioresistant, triple negative tumors have worse local control despite radiation therapy and suggests the prognostic effect of RSI varies with biologic subtype. 48 , 52 …”
Section: Current Landscape Of Rt Genomic Biomarkersmentioning
confidence: 99%