Biological activities of ethyl acetate extract of different parts of<i>Hyssopus angustifolius</i>

Alinezhad, Heshmatollah; Baharfar, Robabeh; Zare, Mahboobeh; Azimi, Razieh; Nabavi, Seyed Fazel; Nabavi, Seyed Mohammad

doi:10.3109/13880209.2012.655859

Cited by 16 publications

(27 citation statements)

References 24 publications

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“…Iron chelating compound can inhibit oxidative stress through iron ion chelation and subsequently inhibit Fenton reactions. This process significantly decreases iron-induced oxidative stress and cellular death in different tissues; for example, in Parkinson's disease, iron chelators prevent hydroxyl generation and inhibit dopaminergic midbrain neurons degeneration (Alinezhad et al, 2012). On the other hand, using synthetic drugs has several limitations such as numerous side effects of these drugs and their cost.…”

Section: Resultsmentioning

confidence: 99%

“…On the other hand, using synthetic drugs has several limitations such as numerous side effects of these drugs and their cost. Therefore, attention has been paid to natural products such as flavonoids that can chelate ferrous ion, and therefore inhibit free radical generation (Alinezhad et al, 2012). In Table 1, ferrous chelating activities of extracts are summarized.…”

Section: Resultsmentioning

confidence: 99%

“…Antioxidant compound can naturalize DPPH radicals through reduction mechanisms that lead to changes in the color of DPPH radical from violet to yellow. It is well known that DPPH scavengers have a wide range of biological activities such as lipid peroxidation inhibitory action, radioprotective activity and so on (Alinezhad et al, 2012). Good antioxidant activity of flower extract probably collates to the presenting of electron donor compounds such as phenols (Alinezhad et al, 2012).…”

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…It is well known that utilization of synthetic antioxidants may associate with different side effects (Alinezhad et al, 2012). Therefore, the need to find natural and safe sources of antioxidants has notably increased (Alinezhad et al, 2012). Plant phenol constituents possess very good antioxidant activity and can protect cells against free radical-induced oxidative stress (Calabrese et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

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Antioxidant activity of different parts ofTetrataenium lasiopetalum

Dehshiri

Aghamollaei

Zarini

et al. 2013

Pharmaceutical Biology

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Context: In Iranian traditional medicine, different species of the genus Tetrataenium are used as antiseptic, spice and food additives. Objective: The present study examined the possible antioxidant effects of hydro-alcoholic extracts of different parts of Tetrataenium lasiopetalum (Boiss.) Manden (Apiaceae). Materials and methods: Laminas, stems, petioles, fruits, peduncles and flowers of T. lasiopetalum were collected, dried and then extracted by ethanol and water (70:30). Antioxidant activities of extracts were examined by employing different in vitro assays, i.e., 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, metal chelating, reducing power activities and hemoglobin-induced linoleic acid system. Also, total phenolic and flavonoid contents of the extracts were evaluated. Results: Hydro-alcoholic extract of T. lasiopetalum flower showed the highest activity in scavenging of DPPH (IC 50 ¼ 170 AE 7 mg/mL). In metal chelating assay, lamina extract possesses a better iron ion chelating activity than other extracts (230 AE 10 mg/mL). Lamina hydro-alcoholic extract demonstrated better activity in reducing the power and hemoglobin-induced linoleic acid system than other parts of T. lasiopetalum. Discussion and conclusion: These results showed the antioxidant activity of different parts of T. lasiopetalum based on its usage in traditional medicine.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%