Biological activities of extracts and metabolites isolated from Anvillea radiata Coss. &amp; Dur. (Asteraceae)

Saoud, D.H.; Jelassi, Awatef; Hlila, Malek Besbes; Goudjil, Mohamed Bilal; Ladjel, Segni; Jannet, Hichem Ben

doi:10.1016/j.sajb.2018.10.033

Cited by 8 publications

(5 citation statements)

References 20 publications

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“…In literature, no study examining the amylase, glucosidase, and cholinesterase inhibition activities of Doronicum species was found. However, the enzyme inhibition activity of many plants from the Asteraceae, which includes also Doronicum , was investigated before (Saoud et al, 2019, Uysal et al, 2018, Ascari et al, 2019, Zengin et al, 2018, Saleem et al, 2019a, Saleem et al, 2019b).…”

Section: Resultsmentioning

confidence: 99%

Antibacterial, antioxidant and enzyme inhibition activity capacities of Doronicum macrolepis (FREYN&SINT): An endemic plant from Turkey

Özcan

2020

Saudi Pharmaceutical Journal

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In the present study, the antioxidant, enzyme inhibition (α-amylase, α-glucosidase, and cholinesterase) and antimicrobial (MIC) activities of three different solvent (ethanol, methanol, or ethyl acetate) extracts of stem, root, and flower of Doronicum macrolepis plant were investigated. In addition to this, the chemical composition and the antimicrobial activity of the essential oil were determined. Antioxidant activity was detected using ABTS and DPPH assays. Antimicrobial activity evaluated by microdilution method against to nineteen microorganisms. Also, enzyme inhibition activities were determined by colorimetric methods. Essential oil of the plant extracted by hydrodistilation and characterized using GC/MS. The antioxidant properties of the flower were determined to be higher than those of the other segments of this plant. Moreover, the total phenolic and flavonoid contents were also found to be higher in the flower parts. The highest enzyme inhibition activity was observed to be α-amylase (221.54 mmol ACAE/g extract) in flower ethylacetate extract, α-glucosidase (15.32 mmol ACAE/g extract) in flower ethanol extract, and cholinesterase (AChE: 2.4 and BChE: 22.35 mg GALE/g extract) in stem ethylacetate extract. Besides them, the antimicrobial activity of the essential oil was found to be higher than the extracts. It showed a high level of inhibition especially on E. coli at 4 µg/ml concentration. Moreover, remarkable inhibition was observed for two candida strains tested. In conclusion, the results suggest that, because of its bioactivity including the antioxidant, antimicrobial, and enzyme inhibition properties, the D. macrolepis can be accepted as a promising and natural source for the industrial applications. The present study is the first study, in which the bioactive components and the antioxidant, antimicrobial, and enzyme inhibition properties of endemic D. macrolepis plant were determined.

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Section: Resultsmentioning

confidence: 99%

Antibacterial, antioxidant and enzyme inhibition activity capacities of Doronicum macrolepis (FREYN&SINT): An endemic plant from Turkey

Özcan

2020

Saudi Pharmaceutical Journal

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“…Several studies have shown the relationship between antioxidant and biological activities of medicinal plants (Saoud et al, 2019;Ashande et al, 2019;Oscar et al, 2020). El Hajaji et al (2010 reported that antioxidant activity was closely related to the phenolic content of extracts from three varieties of Moroccan carob tree leaves.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Phytochemistry and Pharmacology of Ceratonia siliqua L. leaves

GHANEMI¹,

BELARBI²

2021

jnpra

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Ceratonia siliqua commonly known as carob belongs to the Fabaceae (Legumunosae). Its original habitats are the western parts of Asia, but after its domestication, it spread to all Mediterranean Basin and then to the western shores of the Americas, South Africa and southern regions of Australia. This review is devoted to health benefits of the carob leaf which are attributed in particular to its phytochemical constituents such as quercetin and gallic, coumaric, chlorogenic acids. Extracts from carob leaves (CLs) have been investigated for their biological activities including anti-cholestinerase, anti-inflammatory, Antidiarrhoeal, anti-tumor, anti-cancer, antimicrobial, hepatoprotective, nephroprotective, antidiabetic and antiobesity as well as phytochemical profile and nutritive value of the CLs. Hence, extracts from Ceratonia siliqua L. leaves, a huge source of bioactive compounds, exhibit a panoply of biological properties. Thus, leaves can be used as a functional food or as a phyto-pharmaceutical herbal-type product. However, it would be wise to undertake clinical trials to prove the efficacy of carob leaf extracts.

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“…(Asteraceae). Three isolated compounds were tested as well: two epimer germacranolides, 9α-hydroxyparthenolide (26; Figure 2) and 9β-hydroxyparthenolide (27), and the phenolic acid 3,5-O-dicaffeoylquinic acid (28) [46]. The ethyl acetate and n-butanol extracts inhibited the enzyme with IC 50 values of 0.92 mg/mL and 0.81mg/mL, respectively.…”

Section: In Vitro and In Vivo Effects On Carbohydrate Metabolismmentioning

confidence: 99%

A Review of Biologically Active Natural Products from Mediterranean Wild Edible Plants: Benefits in the Treatment of Obesity and Its Related Disorders

2020

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Wild foods constitute an essential component of people’s diets around the world. According to the Food and Agriculture Organization (FAO), over 100 million people in the EU consume wild foods, while 65 million collect some form of wild food themselves. The Mediterranean basin is a biodiversity hotspot of wild edible species. Nowadays, due to the renewed interest in alimurgic plants and the recent findings on the beneficial role of their phytochemical constituents, these species have been defined as “new functional foods”. Research on natural products has recently regained importance with the growing understanding of their biological significance. Botanical food supplements marketed for weight and fat loss in obese subjects will be one of the most important items in marketed nutraceuticals. The aim of this report was to review the phytochemical compounds of Mediterranean wild edible species and their therapeutic potential against obesity and its related disorders. Results on the in vitro and in vivo activity of the most interesting plant extracts and their bioactive components are presented and discussed. The most interesting discoveries on their mechanisms of action are reported as well. Overall, this contribution highlights the importance and beneficial health roles of wild edible species.

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Biological activities of extracts and metabolites isolated from Anvillea radiata Coss. & Dur. (Asteraceae)

Cited by 8 publications

References 20 publications

Antibacterial, antioxidant and enzyme inhibition activity capacities of Doronicum macrolepis (FREYN&SINT): An endemic plant from Turkey

Antibacterial, antioxidant and enzyme inhibition activity capacities of Doronicum macrolepis (FREYN&SINT): An endemic plant from Turkey

Phytochemistry and Pharmacology of Ceratonia siliqua L. leaves

A Review of Biologically Active Natural Products from Mediterranean Wild Edible Plants: Benefits in the Treatment of Obesity and Its Related Disorders

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