Biological activities of lignin hydrolysate-related compounds

The Role of Soluble, Insoluble Fibers and Their Bioactive Compounds in Cancer: A Mini Review

“…From the perspective of biofuels, these compounds are problematic, and can cause downstream loss of product if not removed prior to beginning the fermentative process [53]. In contrast, the same compounds have beneficial properties pertaining to human health, including their role as antioxidants and in cancer prevention, or sometimes their involvement in bacterial cell-to-cell signaling [53]. Lignin is one of the major components of dietary fiber.…”

“…Lignin, another form of insoluble fiber, contains many different chemical species, including ferulic acid, coumaric acid, vanillic acid, vanillin, syringaldehyde and furfural [53]. From the perspective of biofuels, these compounds are problematic, and can cause downstream loss of product if not removed prior to beginning the fermentative process [53].…”

“…Western diet is linked to breast cancer, prostate cancer, coronary heart disease, and colon cancer; which lead to elevation in levels of sex hormones, with decreased SHBG and bioavailability of these hormones [58]. Phytoestrogens have been suggested to have a protective effect on hormone-sensitive cancers [53]. Estrogenic substances present in various lignin foods sources are associated with postmenopausal breast cancer risk too [60].…”

Wheat and Rice Dietary Fiber in Colorectal Cancer Prevention and the Maintenance of Health

“…Ferulic acid and related hydroxycinnamic acids have antioxidant, antimutagenic, and anti-inflammatory effects, and may be involved in cell-cell signaling and gene regulation. [73][74][75][76][77] We have also extended our work on the cell walls of wheat bran layers by comparing the chemical composition and potential anticancer properties of two fractions, one pericarp-rich and one aleurone-rich, obtained by a special milling process. Interestingly, both fractions have different properties that may relate to cancer prevention through different mechanisms.…”

Evaluation of the Safety of Three Phenolic Compounds from <i>Dipteryx alata</i> Vogel with Antiophidian Potential

“…Among them, compounds such as protocatechuic (1, PCA) and vanillic (2, VA) acids, both universal among the angiosperms [1]; and the aldehyde vanillin (3, VN) have closely related structures (Figure 1), which justify the similarity in their biological activity [2].…”