Biological Activities of Plant Food Components: Implications in Human Health

Gentile, Carla

doi:10.3390/foods10020456

Cited by 5 publications

(2 citation statements)

References 10 publications

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“…Among the diverse and complex groups of phenolics that include simple phenols, flavonoids, stilbenes, tannins, and others, phenolic acids are the most distributed in nature. They have been found in various plants, fruits, vegetables, beverages, and agro-food by-products where they contribute to organoleptic attributes such as color, flavor, and odor but their true merits are numerous positive biological activities such as antibacterial, anti-inflammatory, antiallergenic, anticancer, cytotoxic, antitumor, cardioprotective, and antioxidant, which is among the most investigated [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Investigation of Antioxidant Synergisms and Antagonisms among Phenolic Acids in the Model Matrices Using FRAP and ORAC Methods

et al. 2022

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The total antioxidant potential of a sample cannot be predicted from the antioxidant activity of its compounds; thus, scientists usually explain the overall activity through their combined effects (synergistic, antagonistic, or additive). Phenolic compounds are one of the most powerful and widely investigated antioxidants, but there is a lack of information about their molecular interactions. This study aimed to investigate the individual and combined antioxidant activity of equimolar mixtures (binary, ternary, quaternary, and quinary) of 10 phenolic acids (protocatechuic, gentisic, gallic, vanillic, syringic, p-coumaric, caffeic, ferulic, sinapic, and rosmarinic acid) at different concentrations using ferric reducing antioxidant power (FRAP) and oxygen radical absorbance capacity (ORAC) assays. Gallic acid showed the highest antioxidant activity, determined using the FRAP assay (494–5033 µM Fe2+) and rosmarinic acid with the ORAC assay (50–92 µM Trolox Equivalents (TE)), while the lowest antioxidant potential was observed for p-coumaric acid (FRAP 24–113 µM Fe2+ and ORAC 20–33 µM TE). The synergistic effect (by FRAP) in the equimolar mixtures of hydroxybenzoic acids was confirmed for a large number of tested mixtures, especially at low concentrations. All mixtures containing gentisic acid showed a synergistic effect (28–89% difference). Using the ORAC method, only two mixtures of hydroxybenzoic acids showed an antagonistic effect, namely a mixture of gentisic + syringic acids (−24% difference) and gallic + vanillic acids (−30% difference), while all other mixtures showed a synergistic effect in a range of 26–236% difference. Among mixtures of hydroxycinnamic acids, the highest synergistic effect was observed for the mixtures of p-coumaric + ferulic acids and caffeic + sinapic acids with differences of 311% and 211%, respectively. The overall antioxidant activity of phenolic acids could be explained by the number or position of hydroxyl and/or methoxy functional groups as well as the compound concentration, but the influence of other parameters such as dissociation, intramolecular hydrogen bonds, and electron donating or withdrawing effect should not be neglected.

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Section: Introductionmentioning

confidence: 99%

Investigation of Antioxidant Synergisms and Antagonisms among Phenolic Acids in the Model Matrices Using FRAP and ORAC Methods

et al. 2022

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“…It is well known that the non-pathogenic biocontrol bacterium A. radiobacter uses bioremediation to shield seeds from contamination with this harmful bacteria, and it has been considered an effective and relatively inexpensive way to prevent crown gall formation on sui generis plants (Gupta et al 2017). Plants are considered the most important sources of biological activity (Gentile 2021). For the past two decades, researchers have been interested in the species of genus Annona, mainly due to their unique biological properties.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical analysis of Annona atemoya seed extract by HPLC and their ability to inhibit the growth of Agrobacterium tumefaciens

Al-Barhawee

QASIM²,

ABDLLA³

2023

Biodiversitas

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Abstract. Al-Barhawee NIK, Qasim WS, Abdlla YA. 2023. Phytochemical analysis of Annona atemoya seed extract by HPLC and their ability to inhibit the growth of Agrobacterium tumefaciens. Biodiversitas 24: 603-608. The main objective of this study was to determine the effectiveness of Annona atemoya seeds crude alcoholic extract utilizing nine different concentrations (0.0020, 0.0039, 0.0060, 0.0080, and 0.00100 mg/ml). Agrobacterium tumefaciens causes crown gall disease in numerous plant crops causing significant economic losses. Medicinal plants contain chemical compounds (a group of secondary metabolites) known to have antibacterial properties. The result showed that the minimum inhibitory concentration was (0.0313 mg/ml) using agar diffusion technique, while it ranged from (0.0156-0.0313 mg/ml) in the minimal microplate inhibitory concentration test. The crude alcoholic extract of A. atemoya seeds contains alkaloids, flavonoids, glycosides, tannins, phenols, and proteins, but not saponins, based on the results of qualitative analysis of chemical components. HPLC analysis revealed that the extract contained quercitin, rutin, valine, and camphor which were found in the amount of 33.09, 139.39, 0.061, and 7.43 ppm/ml, respectively. Therefore the present finding suggests that A. atemoya seed extract may be used as a biological control to inhibit crown gall formation in plants. This is the first study of the antimicrobial activity of A. atemoya seed alcoholic extract on the growth of plant pathogenic bacteria.

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Bio-based synthesis of silver nanoparticles using leaf extract of Uraria picta (Jacq.) Desv. ex DC.: Characterization and evaluation of its activity against Leishmania donovani

Dixit,

Kumar,

Singh

et al. 2024

Biomass Conv. Bioref.

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Biological Activities of Plant Food Components: Implications in Human Health

Abstract: Scientific data and epidemiological evidence collected over the last fifty years have shown that nutrition plays a decisive role in human health. [...]

Cited by 5 publications

References 10 publications

Investigation of Antioxidant Synergisms and Antagonisms among Phenolic Acids in the Model Matrices Using FRAP and ORAC Methods

Investigation of Antioxidant Synergisms and Antagonisms among Phenolic Acids in the Model Matrices Using FRAP and ORAC Methods

Phytochemical analysis of Annona atemoya seed extract by HPLC and their ability to inhibit the growth of Agrobacterium tumefaciens

Bio-based synthesis of silver nanoparticles using leaf extract of Uraria picta (Jacq.) Desv. ex DC.: Characterization and evaluation of its activity against Leishmania donovani

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