Biological Activities of Schiff Bases and Their Complexes: A Review of Recent Works

Abstract

Schiff bases are the most widely used organic compounds. They have been shown to exhibit a broad range of biological activities, including antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic properties. This review summarizes the synthesis and biological activities of Schiff bases and their complexes.

Erratum to “Novel Facial Conducting Polyamide-Based Dithiophenylidene Cyclyhexanone Moiety Utilized for Selective Cu2+ Sensing”

“…From the chemistry point of view and as reported in the literature, our synthesized PAs are considered as typical materials for detecting Cu 2þ ions rather than other metal ions due to the presence of variable centers of attack toward Cu 2þ ions. [64][65][66][67][68][69][70][71][72][73] The surface selectivity of these new PAs toward Cu 2þ ion comes from its ability to work as an excellent ligand for Cu 2þ ion captured through coordination bond as reported in the literature that nitrogenas well as sulfur-based heteroaromatic compounds are considered as the most important ligands for Cu 2þ ion. Thus, our new PAs are based on thiophene as well as thiazole moieties in the polymer main chain which contains both N and S atoms as well as illustrated previously in Scheme 2.…”

Crystal structure of 1-(4-fluorophenyl)-N-(5-((triphenylstannyl)thio)thiophen-2-yl)methanimine, C27H20FN3S2Sn

“…Recently, attention has been paid to the coordination chemistry of heterocyclic thiol/thione donors, which can give potential access to new complexes with unusual structures and reactivities [7]. The Schiff base ligand also exibits biological activity [8]. However, the organotin complexes also exhibit the biological and commercial applications [9].…”

Synthesis, Characterizations, Biological, and Molecular Docking Studies of Some Amino Acid Schiff Bases with Their Cobalt(II) Complexes

“…The increasing interest in transition metal complexes containing a Schiff base ligand is derived from their well-established role in biological systems as well as their catalytic and pharmaceutical applications [6]. In other hand, Schiff base and their metal complexes have been characterized because of their interesting and important properties as the ability of bind toxic and heavy metal atoms [7], undergoes tautomerism [8], and exhibits catalytic reduction [9], and photochromism [10].…”