2024
DOI: 10.1055/a-2228-4258
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Biological Activity of a Coumarin Derivative on Heart Failure Using an Ischemia/Reperfusion Injury Model

Lauro Figueroa-Valverde,
Marcela Rosas-Nexticapa,
Magdalena Alvarez-Ramirez
et al.

Abstract: Heart failure is a health problem worldwide. There are some drugs for it, including digoxin, spironolactone, captopril, and valsartan, but some of these drugs can produce secondary effects, such as arrhythmia, cough, hyperkalemia, hyponatremia and hypotension. The aim of this research was to evaluate the biological activity of coumarin (2H-chromen-2-one) and its derivatives (3BrAcet-C, 3–4Br-Ph-C, 4-CN-7D-C, 4-M… Show more

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