Biological activity of crude venom from the crown-of-thorns starfish Acanthaster planci.

Abstract

The crude venom (protein concentration 9640ƒÊg/ml) was extracted with buffered saline from the spines of the crown-of-thorns starfish Acanthaster planci and assayed for some biological

Cytotoxic and apoptotic activities of the plancitoxin I from the venom of crown‐of‐thorns starfish (Acanthaster planci) on A375.S2 cells

“…The back of A. planci is covered with many sharp spines (Butzke and Luch, 2010). The accidental sting by venomous crownof-thorns starfish can result in symptoms of illness such as an extremely painful wound, with redness and swelling occurring immediately (Shiomi et al, 1985). The symptoms of nausea and protracted vomiting may also occur (Sato et al, 2008).…”

“…The spines of A. planci are covered with venom that contains several bioactive protein toxins. The crude venom extracted from the spine exhibits multiple biological activities including mouse lethality, hemolytic activity, myonecrotic activity, hemorrhagic activity, capillary permeability-increasing activity, edema-forming activity, phospholipase A2 (PLA2) activity (Shiomi et al, 1985), histamine-releasing activity from mast cells (Shiomi et al, 1989), cardio-vascular actions (Yara et al, 1992;Shiroma et al, 1994) and anticoagulant activity (Karasudani et al, 1996).…”

Isolasi dan Karakterisasi Fosfolipase A2 dari Racun Duri Acanthaster planci Isolat Perairan Papua

“…hasil ekstrak racun dari duri A. planci. Aktifitas biologi itu antara lain : kematian pada tikus, aktifitas hemolitik, aktifitas myonecrotic, aktifitas pendarahan, peningkatan aktifitas permeabilitas kapiler, aktifitas edema, aktifitas fosfolipase-A 2 (PLA 2 ) (Shiomi et al, 1985), aktifitas pelepasan histamin dari mast cell (Shiomi et al, 1989), aktifitas kardiovaskular (Yara et al, 1992;Shiroma et al, 1994) dan aktifitas antikoagulan (Karasudani et al,1996).…”

Chemical constituent analysis of the crown-of-thorns starfish Acanthaster planci and potential utilization value of the starfish as feed ingredient for animals

“…Though it has been confirmed that A. planci has venom (Shiomi et al, 1985;Karasudani et al, 1996), the toxicity of the starfish as food for animals is unknown. To evaluate the possibility of the starfish as the feed component, we analyzed the toxicity of the starfish as the food for mice.…”

“…Thus, A. planci has become a major management issue on coral reefs (Sweatman et al, 2008) that play an important role in marine ecosystem (Souter et al, 2000). Besides its damage to coral reefs, A. planci is notorious for its venom in the spines on body surface (Shiomi et al, 1985;Karasudani et al, 1996). Consequently, many fundamental researches on A. planci have been done, including distribution characters (Marsh and Tsuda, 1973;Yokochi et al, 1991), toxicity and components of venom *Corresponding author.…”