Biological Activity of Deltoside from Allium Nutans L.

Akhov, L. S.; Musienko, M.; Shishova, Y.; Polishuk, V. P.; Oleszek, Wiesław

doi:10.1007/978-94-015-9339-7_23

Cited by 7 publications

(3 citation statements)

References 4 publications

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“…Thus, the biological activity of yucca saponins (1)(2)(3)6) is determined predominantly by spirostanol saponins, the properties of which have been extensively researched (12,13). However, furostanol saponins, which were regarded as transport forms of saponins, not showing biological activities, may possess a wide spectrum of biological activities as shown for Allium deltoside (14). Thus, new furostane saponins identified in this work should be more closely researched with respect to their biological properties.…”

Section: Resultsmentioning

confidence: 88%

Steroidal Saponins of Yucca schidigera Roezl.

Oleszek

Sitek²,

Stochmal³

et al. 2001

J. Agric. Food Chem.

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Eight steroidal saponins have been isolated from Yucca schidigera Roezl. trunk, and their structures were established by spectral (MS and NMR) techniques. These included three novel furostanol glycosides including 3-O-beta-D-glucopyranosyl-(1-->2)-[beta-D-xylopyranosyl-(1-->3)]-beta-D-glucopyranosyl-5 beta(25R)-furostan-3 beta,22 alpha,26-triol 26-O-beta-D-glucopyranoside, 3-O-beta-D-glcopyranosyl-(1-->2)-[beta-D-xylopyranosyl-(1-->3)]-beta-D-glucopyranosyl-5 beta(25R)-furost-20(22)-en-3 beta,26-diol-12-one 26-O-beta-D-glucopyranoside, 3-O-beta-D-glcopyranosyl-(1-->2)-beta-D-glucopyranosyl-5 beta(25R)-furostan-3 beta,22 alpha,26-triol 26-O-beta-D-glucopyranoside, and five known spirostanol glycosides. On the basis of the extraction efficiency, furostanol glycosides made up only 6.8% of total saponins isolated.

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Section: Resultsmentioning

confidence: 88%

Steroidal Saponins of Yucca schidigera Roezl.

Oleszek

Sitek²,

Stochmal³

et al. 2001

J. Agric. Food Chem.

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“…x (Akhov et al, 1999) AT (Akhov et al, 2000) A. ostrowskianum x x x A. porrum x x I, IA (Harmatha et al, 1987) x AF (Carotenuto et al, 1999) of the sugar composition of astersedifolioside A and B shows that a further xylose significantly increases the activity ( Figure 5). Similar results have been reported for related compounds from A. lingulatus, (Shao et al, 1997a,b), where a xylose and a rhamnose increase and decrease, respectively, the cytotoxic activity on human leukemia HL-60 cell line.…”

Section: Saponins From Astermentioning

confidence: 93%

Bioactive Saponins from Allium and Aster Plants

Lanzotti

2005

Phytochem Rev

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Plants belonging to the genera Allium and Aster are widely distributed in nature and have been used as food and/or medicine. Their wide use was mainly due to the medicinal properties attributed to these plants since ancient times, recently supported by epidemiological and laboratory studies. Saponin compounds, responsible for many pharmacological activities, are quite abundant in these plants. Thus, a deep knowledge about the saponin composition of these vegetables appears to be essential and could promote the discovery of new potential leads. As part of our continuing research aimed at the identification of bioactive metabolites, we have addressed our attention to several Allium and Aster species. The study resulted in the isolation of over fifty saponins of furostane, spirostane, cholestane, and oleane-type structures. Some of the isolated compounds exhibited promising antiproliferative, antifungal, and antispasmodic activities. Their structure, distribution and bioactivity will be reported here together with a brief overview of the literature on Allium and Aster saponins.

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“…Furostanol steroidal saponins, also called bidesmosidic steroidal saponins, typically bear two sugar chains at the C‐3 and C‐26 positions of the steroidal skeleton. They are widely distributed in the plant kingdom and have very diverse structures with a broad spectrum of biological and pharmacological activities, such as cytotoxic, antidiabetic and antioxidant activity, etc 1–4. However, little attention was given to this class of compounds until 1966 because of their structural complexity and lability associated with the unique opened F‐ring structure.…”

Section: Methodsmentioning

confidence: 99%