Biological Activity of Extracts in Relationship to Structure of Pure Isolates ofAbutilon indicum

Abstract

The present investigations were undertaken to determine the antibacterial and antifungal activity of the crude extract (CE) of plant parts of Abutilon indicum L. (Malvaceae) in relation to the structure of all previous isolates active and inactive against three Gram-negative bacteria, four Gram-positive rods, and three fungi using agar diffusion method. The results suggested some importance and influence of the hydroxyl groups in the isolates structures such as steroids, flavonoids, glycerides, and coumarins on the activity. The material tested had exhibited excellent activity compared to some of the typical antibiotics against both Gram-positive and Gram-negative bacteria. In summary the results obtained with this plant extract may be considered very promising, indicating the potential for obtaining new antimicrobial agents.

YIELD, YIELD FEATURES, PHYTOCHEMICAL COMPOSITION, ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF Abutilon indicum CULTIVATED UNDER DIFFERENT FERTILIZERS

“…Yasmin et al (2008) reported that the root parts of A. indicum exhibited greater antibacterial activity against Micrococcus luteus, Bacillus subtilis, Escherichia coli and Bacillus licheniformis compared to the leaf and seed extracts, which is consistent with the results of the present study.…”

“…The major components of A. indicum seed oil were identified as linoleic, oleic, stearic and palmitic acids, and this result is consistent with earlier reports (Sharma et al, 2013). These oil components promoted antioxidant activity, as reported in previous studies (Yasmin et al, 2008;Tripathi et al, 2012), and oleic acid may also play an important role in the treatment of heart disease (Singh and Gupta, 2008).…”

“…Therefore, it has been used as a diuretic, pulmonaric, sedative, laxative, antilipidemic and an emollient in folk medicine (Tripathi et al, 2012). The whole plant has also been used to cure blood dysentery and treat allergies, and the seeds are an efficient laxative and expectorant for cough treatment (Yasmin et al, 2008). The leaves have been used to treat throat ulcers, headaches, gonorrhea, and bladder infections and have been employed in the traditional phytotherapy of jaundice and hepatoprotective diseases (Porchezhian and Ansari, 2005).…”

“…Abutilon indicum Sweet is an herbaceous and shrubby plant in the Malvaceae family that grows in tropical and subtropical regions, and it contains saponins, flavonoids, alkaloids and essential oil components such as β-sitosterol, β-amyrin, eudesmol, eugenol, geraniol and caryophyllene (Yasmin et al, 2008). Therefore, it has been used as a diuretic, pulmonaric, sedative, laxative, antilipidemic and an emollient in folk medicine (Tripathi et al, 2012).…”

“…The leaves have been used to treat throat ulcers, headaches, gonorrhea, and bladder infections and have been employed in the traditional phytotherapy of jaundice and hepatoprotective diseases (Porchezhian and Ansari, 2005). A. indicum roots are demulcents and diuretics that are prescribed for fever, chest infection and urethritis (Ponnudurai et al, 2011), and the plant has also been reported to have hepatoprotective (Porchezhian and Ansari, 2005;Tripathi et al, 2012), analgesic, antifertility, antifungal, antibacterial (Tripathi et al, 2012), immunological and anti-inflammatory (Yasmin et al, 2008) activities.…”