Biological activity of extracts of traditional wild medicinal plants from the Balkan Peninsula

Vujanović, Milena; Zengin, Gökhan; Đurović, Saša; Mašković, Pavle; Cvetanović, Aleksandra; Radojković, Marija

doi:10.1016/j.sajb.2018.06.012

Cited by 27 publications

(11 citation statements)

References 55 publications

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“…The inhibitory effect of tyrosinase by A. figarianum extracts are presented in Table 4 and both the extracts showed considerable tyrosinase inhibition, with values of 129.01 mg KAE/g extract for methanol extract and 112.89 mg KAE/g extract for DCM. The observed activity of methanol extract of A. figarianum can be related to the higher concentration of phenolic compounds, and this finding was in agreement with previous studies done by numerous scientists that there is a very strong association between total phenolic content and tyrosinase inhibition [44,45].…”

Section: Enzyme Assayssupporting

confidence: 92%

Secondary Metabolites Profiling, Biological Activities and Computational Studies of Abutilon figarianum Webb (Malvaceae)

et al. 2020

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This research endeavors to inspect the chemical and biological profiling of methanol and dichloromethane (DCM) extracts prepared from Abutilon figarianum Webb. Total bioactive constituents and secondary metabolites were assessed via ultra-high performance liquid chromatography (UHPLC-MS). Biological effects were evaluated via antioxidant and enzymes inhibitory assays. The methanol extract was able to give the highest phenolic (51.92 mg GAE/g extract) and flavonoid (72.59 mg QE/g extract) contents and was found to contain 11 bioactive metabolites, including flavonoid, alkaloid, phenolic and fatty acid derivatives, as accessed by UHPLC-MS analysis. Similarly, the phytochemical profiling of the DCM extract tentatively identified the 12 different secondary metabolites, most of these were fatty acid derivatives. The methanol extract was most active in the radical scavenging, reducing power and total antioxidant power assays, while dichloromethane extract showed the highest metal chelating activity. For enzyme inhibition, the DCM extract showed the highest activity against cholinesterases, glucosidase and amylase, whereas methanol extract was most active against tyrosinase. Docking studies have supported the observed biological activity, where isobergapten showed higher activity against tyrosinase (−7.63 kcal/mol) with inhibition constant (2.55 µM), as opposed to other enzymes. The observed antioxidant and inhibitory potentials of A. figarianum against the studied enzymes tend to endorse this plant as a prospective source of bioactive phytochemicals.

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Section: Enzyme Assayssupporting

confidence: 92%

Secondary Metabolites Profiling, Biological Activities and Computational Studies of Abutilon figarianum Webb (Malvaceae)

et al. 2020

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“…In traditional medicine of Balkan countries, its properties include treatment of inflammations of the skin, open wounds, joint pain, liver diseases, diarrhea, pulmonary disorders, coughs, asthma, abscesses, conjunctivitis, and as a digestive and diuretic agent [27,36,41,42].…”

Section: Traditional Usesmentioning

confidence: 99%

“…Bosnia and Herzegovina liver and stomach diseases [27] Marmahooz Iran headache [73] Dubačac mal Serbia diuretic, stomachic, analgesic, antispasmodic, antibacterial, antifungal, anti-inflammatory, antioxidant activity [41,74] Trava iva Serbia, south abdominal disorders, headaches, tonic, improving appetite, antipyretic, antituberculosis, immune system strengthening [43,75] This document was downloaded for personal use only. Unauthorized distribution is strictly prohibited.…”

Section: Iva Travamentioning

confidence: 99%

A Review of the Phytochemistry, Traditional Uses and Biological Activities of the Essential Oils of Genus Teucrium

et al. 2020

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The genus Teucrium is a large and polymorphic genus of the Lamiaceae family distributed in mild climate zones, particularly in the Mediterranean basin and Central Asia. Studies of nonvolatile constituents of Teucrium species showed that they are a rich source of neo-clerodane diterpenoids, considered as chemotaxonomic markers of the genus. In addition to the nonvolatile metabolites, there has been a large interest in the essential oils of this genus. In this review, a complete survey of the chemical composition and biological properties of the essential oils isolated from Teucrium taxa is provided. In traditional medicine, since ancient times, species of this genus have been widely implemented for their biological properties, including antimicrobial, anti-inflammatory, antispasmodic, insecticidal, anti-malaria, etc. Therefore, a complete review of all of the traditional uses of Teucrium taxa are also reported.

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“…Innovations within the food industry include obtaining new and improving and enhancing the quality of existing products by applying alternative solutions that are mostly related to the use of plants, which are easily available on the Balkan Penninsula. 4 Wild-growing plant species of the Balkan Peninsula have exceptional natural potential and have long been used to treat u, colds, inammation, and similar ailments. Numerous studies are based on the examination of the antioxidant potential of wild-growing plants in order to regulate metabolic processes.…”

Section: Introductionmentioning

confidence: 99%

Elderberry (Sambucus nigra L.) juice as a novel functional product rich in health-promoting compounds

et al. 2020

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Biological activity of extracts of traditional wild medicinal plants from the Balkan Peninsula

Cited by 27 publications

References 55 publications

Secondary Metabolites Profiling, Biological Activities and Computational Studies of Abutilon figarianum Webb (Malvaceae)

Secondary Metabolites Profiling, Biological Activities and Computational Studies of Abutilon figarianum Webb (Malvaceae)

A Review of the Phytochemistry, Traditional Uses and Biological Activities of the Essential Oils of Genus Teucrium

Elderberry (Sambucus nigra L.) juice as a novel functional product rich in health-promoting compounds

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