Biological activity of sulfur nanoparticles in the sulfur-dimethyl sulfoxide-water system

Abstract

For the first time a sulfur solution in dimethyl sulfoxide (DMSO) with concentration of 1.592 g/L [1] was used to prepare sulfur nanoparticles (nanosulfur). Synthesis and stabilization of colloidal sulfur particles was carried out at 298K (25 °C) by diluting the sulfur solution in DMSO with water from 10 to 1000 times. The stable sizes of nanosulfur measured by dynamic light scattering were ~ 100 nm. The results were confirmed both qualitatively and quantitatively using X-ray and electron microscopy methods. Raman spectroscopy also confirmed the presence of sulfur. The kinetics of changes in the size of sulfur nanoparticles, depending on the degree of aqueous dilution of the initial sulfur solution in DMSO was investigated. The antibacterial activity of the nanosulfur on the phytopathogenic bacterium Erwinia amylovora and fungus Fusarium solani was tested. The study of antimicrobial activity was carried out using two methods, and the results revealed the ability of the synthesized nanosulphur to suppress pathogenic microorganisms.

Mechanochemical recrystallization: Forgotten basics and new possibilities

“…The closest in technical essence to the proposed method of "mechanochemical recrystallization" are the solution methods for obtaining nanosulfur [32,33] and sulfur-containing nanocomposites S / AgX [29,30,34] using DMSO. The disadvantage of this method is the impossibility of S / AgX synthesis with a controlled sulfur content.…”