SUMMARY This study aimed to evaluate the bio-economic performance in confinement crossbred goats from different genetic groups. Were used 30 goats, crossbred (F1) intact male, 10 goats Boer x SPRD (undefined breed), 10 x Savannah SPRD and 10 Oberhasli x SPRD, with an average weight of 15 kg and an average age of 100 days. The initial weight was evaluated, final body weight, average daily gain, total weight gain, dry matter intake, water intake, feed conversion and days on feed. As an economic indicator was calculated gross profit margin (MB), the average dry matter intake, the confinement period, the cost of each diet and the cost of vaccines and medicines. We used the 5% Tukey test for comparisons between treatment means. For the variables weight gain, dry matter intake, water intake and body condition score averages observed did not differ between the genetic groups. There was significant effect (P> 0.05) of genetic groups on days on feed. The biological performance of the goats finished in feedlot was not influenced by genetic group. In bioeconomic analysis was no significant difference (P> 0.05) between the evaluated racial groups. Gross profit margin was negative for the mestizos Pardo Alpine x SPRD. The cross between the Boer breed and without defined breed results in premature animals, reaching slaughter weights with reduced confinement period. In the feedlot finishing system crossbred Boer goats x SPRD showed better economic performance, providing greater profitability to the creator.