The traditional regional focus of evolutionary anthropology—typically defined as places where hominin fossils, nonhuman primates, and non‐western populations reside—forms the basis of much evolutionary anthropological research. Using the highly biodiverse temperate region of Appalachia as an example, we suggest that evolutionary anthropologists have much to gain by stepping outside of this traditional geographic area. Being purposely provocative, we argue that evolutionary anthropologists might also benefit from conducting research in Appalachia and other temperate ecosystems. We briefly discuss multiple areas of study—including studies of seed dispersal, functional redundancy, convergent evolution, human behavioral ecology, and conservation—and how they can be considered within the purview of integrative and evolutionary anthropology. We also highlight broader impacts to higher education that evolutionary anthropologists can help promote by working in local ecosystems.