Biological and Non-Conventional Synthesis of Zinc Oxide Nanoparticles (ZnO-NPs): Their Potential Applications

Abstract

Zinc oxide nanoparticles (ZnO-NPs) are odorless, white, and insoluble in water and alcohol. There are various applications for ZnO due to its unique semiconducting, piezoelectric, and optical features. Biodegradability and low toxicity are important properties of ZnO nonmaterial. The OH groups on the ZnO surface allow different surface decorating molecules to easily functionalize it. Mineralized in muscle, brain, skin, bone, and other tissues, zinc is a necessary mineral. It is a major component of most enzyme systems and is involved in protein and macromolecule production, neurogenesis, and hematopoiesis, among other functions. Due to its small particle size, Nano-ZnO is easily absorbed by the body. So-called nano-ZnO is commonly utilized in food additives. Chemical surface properties, particle shape, size distribution, and particle reactivity in solution all influence the biological activity of nanoparticles. Determining the morphology, size, and functioning of nanoparticles with regulated structures is critical for biological applications. In this review article, biological and non-conventional synthesis and applications of ZnO-NPs are highlighted in terms of their biological activity. ZnO-NPs have shown therapeutic activity against cancer, diabetes, microbial infection, inflammation, and potential antioxidant activity, which can be used as drug carriers, imaging tools, and biosensors.

Recent Advances in Nanotechnology-Based Drug Delivery Systems for the Diagnosis and Treatment of Reproductive Disorders

“…The developed combination has shown significant promise as a therapeutic approach for the treatment of male erectile dysfunction. The administration of avanafil, a key pharmaceutical compound employed for managing erectile dysfunction, via a hydrogel film consisting of solid lipid nanoparticles led to notable improvements in both its bioavailability and transdermal distribution …”

“…The administration of avanafil, a key pharmaceutical compound employed for managing erectile dysfunction, via a hydrogel film consisting of solid lipid nanoparticles led to notable improvements in both its bioavailability and transdermal distribution. 233…”

Synthetization and Characterization of Zinc Oxide Nanoparticles by X- Ray Diffractometry (XRD), Fourier Transforms, Infra-Red Spectroscopy (FT-IR), Scanning Electron Microscopy (SEM) and Antibacterial Activity Test

“…Zinc oxide nanoparticles have acquire much more importance in the recent years due to their attractive and outstanding properties such as chemical [12], mechanical and thermal stability, high potency [13], high electrochemical coupling coefficient, broad range of Ultraviolet radiation absorption, transparency for visible light, increased selectivity [14], large exciton binding energy [15],high electrical, optical properties [16], low toxicity [17], high electron mobility and, strong room temperature luminescence [3], high photosensitivity [18], biocompatibility [19], biodegradability, high solubility [20] , inexpensive and earth abundant compound [21]. It has been shown that zinc oxide, both in bulk form and as well as nanoparticles, has biodegradability.…”

Antibacterial and photocatalytic effects of newly synthesized zinc oxide nanoparticles derived from Mongolian honey

“…ZnONPs are still synthesized and produced by conventional (physical, chemical and 39 biological methods) and unconventional methods (reactor based method) [5]. Zinc oxide is recognized as a safe material that is non-toxic, bio-safe and bio-compatible [6].…”