Biological and psychological rhythms: An integrative approach to rhythm disturbances in autistic disorder

Botbol, Michel; Cabon, Philippe; Kermarrec, Solenn; Tordjman, Sylvie

doi:10.1016/j.jphysparis.2013.03.009

Cited by 9 publications

(5 citation statements)

References 102 publications

(106 reference statements)

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“…-Sleep disorders [delayed sleep phase syndrome (Skene et al, 1999), non-24 h sleep/ wake disorder and sleep/wake schedule disorder (Dagan & Abadi, 2001;Uchiyama & Lockley, 2015), recurrent hypersomnia (Billiard et al, 2011), SW sleep disorder (Schwartz & Roth, 2006)] -SW intolerance (Andlauer & Reinberg, 1979;Reinberg et al, 1983Reinberg et al, , 1988) -Delirium (Fitzgerald et al, 2013) -Peptic ulcer disease (Moore & Merki, 1997;Moore & Smolensky, 1991) -Affective disorders [depression (BicakovaRocher et al, 1996;Rosenwasser & WirtzJustice, 1997;Salgado-Delgado et al, 2011), mania (Klemfuss & Kripke, 1989), bipolar disorder (Abreu & Bragança, 2015)] -Parkinson's disease (Bordet et al, 2003;Fertl et al, 1991;Willison et al, 2013) -Autism spectrum disorder (Botbol et al, 2013;Tordjman et al, 2015) -Smith-Magenis syndrome (Chen et al, 2015) -Fatal familial insomnia [autosomal dominant prion brain disease (Montagna et al, 1995;Portaluppi et al, 1994aPortaluppi et al, , 1994bPortaluppi et al, , 1995] -Kidney failure, especially end-stage disease (Biasioli et al, 1988;Farfel et al, 1978;Hillier et al, 1980;Koch et al, 2009;Mojón et al, 2013;Portaluppi et al, 1990;Raff & Trivedi, 2012;Russcher et al, 2015;Wheatley et al, 1989) -Pulm...…”

Section: Discussionmentioning

confidence: 99%

Circadian disruption: New clinical perspective of disease pathology and basis for chronotherapeutic intervention

Smolensky

Hermida

Reinberg

et al. 2016

Chronobiology International

155

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Biological processes are organized in time as innate rhythms defined by the period (τ), phase (peak [Φ] and trough time), amplitude (A, peak-trough difference) and mean level. The human time structure in its entirety is comprised of ultradian (τ < 20 h), circadian (20 h > τ < 28 h) and infradian (τ > 28 h) bioperiodicities. The circadian time structure (CTS) of human beings, which is more complicated than in lower animals, is orchestrated and staged by a brain central multioscillator system that includes a prominent pacemaker - the suprachiasmatic nuclei of the hypothalamus. Additional pacemaker activities are provided by the pineal hormone melatonin, which circulates during the nighttime, and the left and right cerebral cortices. Under ordinary circumstances this system coordinates the τ and Φ of rhythms driven by subservient peripheral cell, tissue and organ clock networks. Cyclic environmental, feeding and social time cues synchronize the endogenous 24 h clocks and rhythms. Accordingly, processes and functions of the internal environment are integrated in time for maximum biological efficiency, and they are also organized and synchronized in time to the external environment to ensure optimal performance and response to challenge. Artificial light at night (ALAN) exposure can alter the CTS as can night work, which, like rapid transmeridian displacement by air travel, necessitates realignment of the Φ of the multitude of 24 h rhythms. In 2001, Stevens and Rea coined the phrase "circadian disruption" (CD) to label the CTS misalignment induced by ALAN and shift work (SW) as a potential pathologic mechanism of the increased risk for cancer and other medical conditions. Current concerns relating to the effects of ALAN exposure on the CTS motivated us to renew our long-standing interest in the possible role of CD in the etiopathology of common human diseases and patient care. A surprisingly large number of medical conditions involve CD: adrenal insufficiency; nocturia; sleep-time non-dipping and rising blood pressure 24 h patterns (nocturnal hypertension); delayed sleep phase syndrome, non-24 h sleep/wake disorder; recurrent hypersomnia; SW intolerance; delirium; peptic ulcer disease; kidney failure; depression; mania; bipolar disorder; Parkinson's disease; Smith-Magenis syndrome; fatal familial insomnia syndrome; autism spectrum disorder; asthma; byssinosis; cancers; hand, foot and mouth disease; post-operative state; and ICU outcome. Poorly conceived medical interventions, for example nighttime dosing of synthetic corticosteroids and certain β-antagonists and cyclic nocturnal enteral or parenteral nutrition, plus lifestyle habits, including atypical eating times and chronic alcohol consumption, also can be causal of CD. Just as surprisingly are the many proven chronotherapeutic strategies available today to manage the CD of several of these medical conditions. In clinical medicine, CD seems to be a common, yet mostly unrecognized, pathologic mechanism of human disease as are the many effective chronotherapeutic int...

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Section: Discussionmentioning

confidence: 99%

Circadian disruption: New clinical perspective of disease pathology and basis for chronotherapeutic intervention

Smolensky

Hermida

Reinberg

et al. 2016

Chronobiology International

155

View full text Add to dashboard Cite

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“…Another emerging hypothesis for intrinsic causes of insomnia in children with ASD includes circadian-relevant gene anomalies resulting in biological and behavioral rhythm disturbances [45, 46, 31, 11, 47, 48]. In humans, sleep and wakefulness are regulated in part by an endogenous circadian clock, the suprachiasmatic nucleus in the brain [11].…”

Section: What Are the Hypotheses For The High Prevalence Of Insomnia mentioning

confidence: 99%

Sleep in Children with Autism Spectrum Disorder

Souders

Zavodny

Eriksen

et al. 2017

Curr Psychiatry Rep

208

143

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The purposes of this paper are to provide an overview of the state of the science of sleep in children with autism spectrum disorder (ASD), present hypotheses for the high prevalence of insomnia in children with ASD, and present a practice pathway for promoting optimal sleep. Approximately two thirds of children with ASD have chronic insomnia, and to date, the strongest evidence on promoting sleep is for sleep education, environmental changes, behavioral interventions, and exogenous melatonin. The Sleep Committee of the Autism Treatment Network (ATN) developed a practice pathway, based on expert consensus, to capture best practices for screening, identification, and treatment for sleep problems in ASD in 2012. An exemplar case is presented to integrate key constructs of the practice pathway and address arousal and sensory dysregulation in a child with ASD and anxiety disorder. This paper concludes with next steps for dissemination of the practice pathway and future directions for research of sleep problems in ASD.

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“…Human beings both act and interact in time. Emphasizing the temporal character of interaction, the experience of time has repeatedly been linked to intersubjectivity (Fuchs, 2001;Wyllie, 2005;Vogeley & Kupke, 2007;Botbol et al, 2013;Fuchs, 2013;Mölder, 2016;Nielsen, 2017), and psychopathological disturbances of time experience repeatedly have been associated with disturbances of intersubjectivity on a temporal level (Fuchs, 2005;Wyllie, 2005;Fuchs, 2013;Moskalewicz, 2015a;Moskalewicz, 2015b;Stanghellini et al 2016;Fuchs & van Duppen, 2017;Nielsen, 2017). These observations and hypotheses suggest an intricate relationship between time experience and social behavior.…”

Section: Introductionmentioning

confidence: 99%

Interrupted Time Experience in Autism Spectrum Disorder: Empirical Evidence from Content Analysis

Vogel

Falter‐Wagner

Schoofs

et al. 2018

J Autism Dev Disord

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Although the experience of time is of central relevance for psychopathology, qualitative approaches to study the inner experience of time have been largely neglected in autism research. We present results from qualitative data acquired from 26 adults with high functioning autism spectrum disorder (ASD). Employing inductive content analysis we identified a distinct pattern of interrupted time experience in ASD. Individuals with ASD seemed to implement structured and routine behavior by future planning to guarantee that the present passed uninterrupted. We reason that the success of corresponding compensatory mechanisms determines the development of distress and noticeable symptoms. Considering recent theories on Bayesian perceptual inference we relate the syndrome of interrupted time experience to the putative neuronal mechanisms underlying time experience.

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Biological and psychological rhythms: An integrative approach to rhythm disturbances in autistic disorder

Cited by 9 publications

References 102 publications

Circadian disruption: New clinical perspective of disease pathology and basis for chronotherapeutic intervention

Circadian disruption: New clinical perspective of disease pathology and basis for chronotherapeutic intervention

Sleep in Children with Autism Spectrum Disorder

Interrupted Time Experience in Autism Spectrum Disorder: Empirical Evidence from Content Analysis

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