Biological applications of quantum dots

A B S T R A C TAdvancements in nanoscience enabled the synthesis of a diverse array of engineered nanomaterials. The precise control of the composition and quality of such nanomaterials is required to ensure their eventual successful application. Also importantly, the potentially adverse environmental and/or human health effects resulting from exposure to nanoparticles (NPs) is still a critical but underexplored research area. To understand and assess the potentially harmful effects of NPs a proper knowledge of their physicochemical properties is required.Among the different available analytical tools for the characterization and quantification of engineered inorganic NPs, mass spectrometry (MS) offers outstanding capabilities. The analytical capabilities of different MS-based techniques, including elemental and molecular detection, and hybrid tools derived from their coupling with different separation approaches, to identify, characterize and quantify NPs is here revised. A forward look into trends on the use of MS for more complete chemical analysis of engineered inorganic NPs is finally attempted.

show abstract

“…b) provide adequate reactive groups in the NPs surface for further bioconjugations to other biomolecules [58].…”

Section: Molecular Mass Spectrometrymentioning

confidence: 99%

Mass spectrometry for the characterization and quantification of engineered inorganic nanoparticles

Costa‐Fernández

Menéndez-Miranda

Bouzas-Ramos

et al. 2016

TrAC Trends in Analytical Chemistry

View full text Add to dashboard Cite

show abstract

“…Presently, there are numerous comprehensive reviews that have focused broadly on the chemistry of group II-VI, IV-VI and III-V QDs, such as their design, synthesis, surface modifications and optical properties which readers of this article can refer to [58][59][60][61][62][63][64][65][66][67]. However, it is important to discuss certain photophysical properties of QDs that influence their surface chemistry towards sensor development in order to convey a clearer understanding of the behavioural properties of different QD-based fluorescent probes for ROS/RNS.…”

Section: General Considerations For a Qds Fluorescent Sensormentioning

confidence: 99%

Challenges and advances in quantum dot fluorescent probes to detect reactive oxygen and nitrogen species: A review

Adegoke

Forbes

2015

Analytica Chimica Acta

View full text Add to dashboard Cite

show abstract

“…[48][49][50] Organic fluorophores generally result in insufficient fluorescence emission for adequate time resolution for single molecule tracking, 51 and may suffer from considerable photobleaching after only a few minutes illumination. 52 Conjugation to micron-sized particles, though more easily trackable by optical microscopy, would involve a significant load on the biomolecule potentially resulting in sedimentation rather than Brownian diffusion. Nanoparticles (NPs), on the other hand, are comparable in size to many proteins.…”

Section: 1) Frommentioning

confidence: 99%

Nanopropulsion by Biocatalytic Self-Assembly

et al. 2014

View full text Add to dashboard Cite

This version is available at https://strathprints.strath.ac.uk/50864/ Strathprints is designed to allow users to access the research output of the University of Strathclyde. Unless otherwise explicitly stated on the manuscript, Copyright © and Moral Rights for the papers on this site are retained by the individual authors and/or other copyright owners. Please check the manuscript for details of any other licences that may have been applied. You may not engage in further distribution of the material for any profitmaking activities or any commercial gain. You may freely distribute both the url (https://strathprints.strath.ac.uk/) and the content of this paper for research or private study, educational, or not-for-profit purposes without prior permission or charge.Any correspondence concerning this service should be sent to the Strathprints administrator: strathprints@strath.ac.ukThe Strathprints institutional repository (https://strathprints.strath.ac.uk) is a digital archive of University of Strathclyde research outputs. It has been developed to disseminate open access research outputs, expose data about those outputs, and enable the management and persistent access to Strathclyde's intellectual output. 1Nanopropulsion by Biocatalytic Self-Assembly

show abstract

Biological applications of quantum dots

Cited by 1,016 publications

References 151 publications

Mass spectrometry for the characterization and quantification of engineered inorganic nanoparticles

Mass spectrometry for the characterization and quantification of engineered inorganic nanoparticles

Challenges and advances in quantum dot fluorescent probes to detect reactive oxygen and nitrogen species: A review

Nanopropulsion by Biocatalytic Self-Assembly

Contact Info

Product

Resources

About