Biological aspects of new organotin(IV) compounds of 3-maleimidopropionic acid

Diorganotin (IV) complexes with 4-nitro-N-phthaloyl-glycine: Synthesis, characterization, antitumor activity and DNA-binding studies

“…The signal of carboxyl hydrogen atom, which was appeared at 13.37 ppm in the spectrum of ligand, was absent in the spectrum of complexes 1-2 when the carboxylate coordinates with Sn. The butyl and methyl protons, which substituted on tin, exhibited a single triplet resonance, which indicated one tin site, as reported [18]. By comparing integral values of ligand resonances to integral values of the di-n-butyltin/di-methyltin moiety resonances, the ratios of ligand to di-n-butyltin/di-methyltin moiety can be quantified, respectively.…”

Synthesis, structural characterization and bioassay screening of dimeric bis[dicarboxylatotetraorganodistannoxanes]

“…of NMR signals for bis(pyrazol-1-yl)acetate groups in the two compounds is observed, possibly due to the result of the fast exchange in the coordination behavior of carboxylate groups attached to the endo-and exo-cyclic tin atoms. 8 In the solid state, molecule 2 forms a dimer through intermolecular O-H· · ·N hydrogen bonds (Fig. 1).…”

Heptacoordinate Tin(IV) Compounds Derived from Pyridine Schiff Bases: Synthesis, Characterization, in Vitro Cytotoxicity, Anti-inflammatory and Antioxidant Activity

“…3) Among the most studied organotin(IV) complexes a special emphasis has been placed on the study of carboxylates as potential metallotherapeutic drugs, 4) however, a wide spectrum of biological activities such as anti-microbial, [5][6][7][8][9][10] anti-inflammatory, [11][12][13][14][15] anti-fungal, 14) cardiovascular, 5,10,16,17) anti-tuberculosis 18,19) and biocide among others remains a subject of intense study. 20) Schiff bases are of paramount importance as ligands in metal coordination chemistry as they form stable complexes with most of transition metals.…”