2020
DOI: 10.3390/v12111306
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Biological Characteristics and Patterns of Codon Usage Evolution for the African Genotype Zika Virus

Abstract: We investigated temporal trends of codon usage changes for different host species to determine their importance in Zika virus (ZIKV) evolution. Viral spillover resulting from the potential of codon adaptation to host genome was also assessed for the African genotype ZIKV in comparison to the Asian genotype. To improve our understanding on its zoonotic maintenance, we evaluated in vitro the biological properties of the African genotype ZIKV in vertebrate and mosquito cell lines. Analyses were performed in compa… Show more

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