Biological Control of Mosquito-Borne Diseases: The Potential of<i>Wolbachia</i>-Based Interventions in an IVM Framework

Niang, El Hadji Amadou; Basséne, Hubert; Fénollar, Florence; Mediannikov, Oleg

doi:10.1155/2018/1470459

Cited by 46 publications

(43 citation statements)

References 84 publications

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“…This information is essential for keeping track of mosquito-vectored diseases, but lacks any further insight into the processes that underlie or affect the mosquito-pathogen interactions. For this reason, research focuses are shifting to the mechanisms involved in vectors' infection by pathogens and the development of new vector control strategies (Niang et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Methodological Insight Into Mosquito Microbiome Studies

Rodríguez‐Ruano

Juhaňáková

Vávra

et al. 2020

Front. Cell. Infect. Microbiol.

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Symbiotic bacteria affect competence for pathogen transmission in insect vectors, including mosquitoes. However, knowledge on mosquito-microbiome-pathogen interactions remains limited, largely due to methodological reasons. The current, cost-effective practice of sample pooling used in mosquito surveillance and epidemiology prevents correlation of individual traits (i.e., microbiome profile) and infection status. Moreover, many mosquito studies employ laboratory-reared colonies that do not necessarily reflect the natural microbiome composition and variation in wild populations. As a consequence, epidemiological and microbiome studies in mosquitoes are to some extent uncoupled, and the interactions among pathogens, microbiomes, and natural mosquito populations remain poorly understood. This study focuses on the effect the pooling practice poses on mosquito microbiome profiles, and tests different approaches to find an optimized low-cost methodology for extensive sampling while allowing for accurate, individual-level microbiome studies. We tested the effect of pooling by comparing wild-caught, individually processed mosquitoes with pooled samples. With individual mosquitoes, we also tested two methodological aspects that directly affect the cost and feasibility of broad-scale molecular studies: sample preservation and tissue dissection. Pooling affected both alpha-and beta-diversity measures of the microbiome, highlighting the importance of using individual samples when possible. Both RNA and DNA yields were higher when using inexpensive reagents such as NAP (nucleic acid preservation) buffer or absolute ethanol, without freezing for short-term storage. Microbiome alpha-and beta-diversity did not show overall significant differences between the tested treatments compared to the controls (freshly extracted samples or dissected guts). However, the use of standardized protocols is highly recommended to avoid methodological bias in the data.

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Section: Introductionmentioning

confidence: 99%

Methodological Insight Into Mosquito Microbiome Studies

Rodríguez‐Ruano

Juhaňáková

Vávra

et al. 2020

Front. Cell. Infect. Microbiol.

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“…Mosquito symbiont-associated bacteria may exert a pathogenic effect on their host, interfering with its reproduction and also reducing vector competence [144]. Wolbachia are endosymbiotic bacteria that naturally infect approximately 40% of insect species [145,146], and Wolbachia pipientis is a unique valid species of the genus [147].…”

Section: Wolbachia Sppmentioning

confidence: 99%

“…aegypti [144,145,[148][149][150]. This maternally transmitted bacterium allowing the invasion of host populations can induce feminisation of males (turning genetic males into females), parthenogenesis (reproduction without males) [144], and cytoplasmic incompatibility, leading to the generation of inviable offspring when a Wolbachia-infected male mates with an uninfected female, but not in the contrary case [145]. Successfully used in Myanmar in the 1960s to eradicate Cx.…”

Section: Wolbachia Sppmentioning

confidence: 99%

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Mosquito-Borne Diseases Emergence/Resurgence and How to Effectively Control It Biologically

2020

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Deadly pathogens and parasites are transmitted by vectors and the mosquito is considered the most threatening vector in public health, transmitting these pathogens to humans and animals. We are currently witnessing the emergence/resurgence in new regions/populations of the most important mosquito-borne diseases, such as arboviruses and malaria. This resurgence may be the consequence of numerous complex parameters, but the major cause remains the mismanagement of insecticide use and the emergence of resistance. Biological control programmes have rendered promising results but several highly effective techniques, such as genetic manipulation, remain insufficiently considered as a control mechanism. Currently, new strategies based on attractive toxic sugar baits and new agents, such as Wolbachia and Asaia, are being intensively studied for potential use as alternatives to chemicals. Research into new insecticides, Insect Growth Regulators, and repellent compounds is pressing, and the improvement of biological strategies may provide key solutions to prevent outbreaks, decrease the danger to at-risk populations, and mitigate resistance.Pathogens 2020, 9, 310 2 of 26 are not used at all, and those that are still in the test or design phase but are very promising, which we suggest to be considered in the biological control of mosquito-borne diseases.

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“…Dangerous diseases due to mosquito bite like dengue, malaria and chikungunya hit over 1.13 million people in the country last year [67]. Global warming also increases the growth of mosquitoes and thus the growth in disease like malaria, yellow fever and dengue fever [68]. Pomegranate peel dyed cotton fabric using different conc.…”

Section: Mosquito Repellentmentioning

confidence: 99%

Functional Properties of Natural Dyed Textiles

Pargai¹,

Jahan²,

Gahlot³

2020

Chemistry and Technology of Natural and Synthetic Dyes and Pigments

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Recently, due to harmful effect of climate change and other environmental concerns, the interest towards natural dyes has gained momentum. Presently in this high technological era, only aesthetic appeal of natural dyes could not get full attention of consumers. A consumer is attracted towards a type of product which is not only aesthetic but also have some functional properties. Hence considering this functional aspect, various researches are being carried out to find out the new dimensions of natural dyes. Colours and other functional properties can be achieved by various synthetic agents, but the exploration of new functional properties of natural dyes would be beneficial and relevant for the present as well as for the future. This chapter compiles all functional aspects of natural dyes which are related to adding functional properties such as antimicrobial, UV protection, insect repellent, etc. to textiles which can protect the human being from various kinds of harmful effects of surroundings such as UV radiation, microbes, bacteria and other harmful insects. This chapter will not only deal with available methods for analysis of these functional properties of natural dyes but also explore the reason for functional properties of natural dyes.

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Biological Control of Mosquito-Borne Diseases: The Potential ofWolbachia-Based Interventions in an IVM Framework

Cited by 46 publications

References 84 publications

Methodological Insight Into Mosquito Microbiome Studies

Methodological Insight Into Mosquito Microbiome Studies

Mosquito-Borne Diseases Emergence/Resurgence and How to Effectively Control It Biologically

Functional Properties of Natural Dyed Textiles

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