Biological detoxification of zearalenone by Aspergillus niger strain FS10

Sun, Xiulan; He, Xingxing; Xue, Kathy S.; Li, Yun; Xu, Dan; Qian, He

doi:10.1016/j.fct.2014.06.021

Cited by 58 publications

(33 citation statements)

References 39 publications

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“…In addition, the BLYES showed that these strains ceased the hormonal (estrogenic) effect of ZON. This degrading potential exceeded the degrading values of the Aspergillus niger FS10 strain in the experiment of Sun et al (2014) and the values of the representatives of some Rhodococcus species in the study of Cserh ati et al (2013). However, our high degrading potential values were similar to the results of other Rhodocoocus strains in the study of Krifaton et al (2013).…”

Section: Discussioncontrasting

confidence: 45%

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Biodegradation of aflatoxin-B1 and zearalenone by Streptomyces sp. collection

Harkai

Szabó

Cserháti

et al. 2016

International Biodeterioration & Biodegradation

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a b s t r a c tAflatoxin B1 (AFB1) and zearalenone (ZON) are hazardous mycotoxins. AFB1 has cytotoxic, mutagenic and carcinogenic effects, whereas ZON can disrupt the endocrine system. Biodegradation by microbes is an effective method to eliminate these hazardous toxins. The aim of this work was to screen AFB1 and ZON biodegrading potential of one hundred and twenty-four Streptomyces strains deposited in the Actinomycetes strain collection of the Department of Environmental Safety and Ecotoxicology. Two different biotests were used for screening purposes: SOS-Chromotest was used to monitor genotoxicity and select microorganisms with the best AFB1 degrading potential. Estrogenic effect of ZON was measured with a yeast based bioluminescent test including human estrogen receptors Bioluminescent Yeast Estrogen System (BLYES). Biodegradation experiments were conducted with 1 mg l À1 AFB1 and 1 mg l À1 ZON concentration. On the base of the results, ten strains were selected for biodegradation experiments and Enzyme-linked Immunosorbent Assay tests (ELISA). The results of these tests Streptomyces cacaoi subsp. asoensis (K234) strain degraded AFB1 over 88 per cent and totally eliminated genotoxicity. Two strains of Streptomyces rimosus (K145, K189) degraded almost total amount of ZON and estrogenicity was not detected besides that.

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Section: Discussioncontrasting

confidence: 45%

“…ZON getting into human and animal body may cause early sexual maturity, miscarriage, underdeveloped embryos (Bennett and Klich, 2003;Farnworth and Trenholm, 1983;Green et al, 1990). ZON is a common contaminant in maize and hay, therefore, elimination of this mycotoxin is an important object in agricultural detoxification (Sun et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Biodegradation of aflatoxin-B1 and zearalenone by Streptomyces sp. collection

Harkai

Szabó

Cserháti

et al. 2016

International Biodeterioration & Biodegradation

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“…In some cases, however, the biotransformation product is not detectable through chemical analysis methods, and indirect methods must therefore be adopted to distinguish between adsorption and biotransformation. The involvement of an enzymatic reaction, rather than simple binding, is evidenced by the loss of biotransformation activity following heat or acid-inactivation of cells or in an extracellular extract treated with enzyme inactivating agents, such as proteinase K, SDS or EDTA [12,15,19,98,99]. Furthermore, the subcellular location of active components responsible for biotransformation can be identified by comparing activities in the whole cell culture, extracellular extract (by centrifugation) and cytoplasmic extract (by cell lysis) [25,27,34,45,50,59,88,99].…”

Section: Strategies and Methodologiesmentioning

confidence: 99%

Strategies and Methodologies for Developing Microbial Detoxification Systems to Mitigate Mycotoxins

Zhu

Hassan

Lepp

et al. 2017

Toxins

100

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Mycotoxins, the secondary metabolites of mycotoxigenic fungi, have been found in almost all agricultural commodities worldwide, causing enormous economic losses in livestock production and severe human health problems. Compared to traditional physical adsorption and chemical reactions, interest in biological detoxification methods that are environmentally sound, safe and highly efficient has seen a significant increase in recent years. However, researchers in this field have been facing tremendous unexpected challenges and are eager to find solutions. This review summarizes and assesses the research strategies and methodologies in each phase of the development of microbiological solutions for mycotoxin mitigation. These include screening of functional microbial consortia from natural samples, isolation and identification of single colonies with biotransformation activity, investigation of the physiological characteristics of isolated strains, identification and assessment of the toxicities of biotransformation products, purification of functional enzymes and the application of mycotoxin decontamination to feed/food production. A full understanding and appropriate application of this tool box should be helpful towards the development of novel microbiological solutions on mycotoxin detoxification.

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“…Zearalenone (ZEA) is a widely distributed nonsteroidal estrogenic mycotoxin. It is a resorsilic acid lactone derivative and is produced by several fungal species within the Fusarium genus …”

Section: Introductionmentioning

confidence: 99%

Biosorptive detoxification of zearalenone biotoxin by surface‐modified renewable biomass: process dynamics and application

et al. 2018

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BACKGROUND Contamination of food, feed, beverages and even drinking water with biotoxins is a growing global concern because of their potential health risks. In this work, surface‐modified sugar beet pulp waste was used for the biosorptive removal of zearalenone biotoxin from contaminated aquatic media. RESULTS Infrared, Boehm titration, BET (Brunauer–Emmett–Teller) surface area and point of zero charge analysis were employed for surface characterization. Kinetic and equilibrium studies showed that biotoxin biosorption was well predicted by the pseudo‐second‐order kinetic model and the Langmuir isotherm model. Zearalenone was removed from the solution over a wide pH range (3.0–8.0) and within a short time (15 min). Maximum uptake capacity of modified biomass was recorded as 23.30 ± 0.17 g kg−1. Highest removal yield in a dynamic flow mode (94.56 ± 0.13%) was achieved at 2 mL min−1 flow rate using 30 mg biosorbent. Regeneration experiments revealed high reusability potential of suggested biosorbent. Moreover, its application potential was tested in spiked samples of malt, beer and canned corn liquid. CONCLUSION Detoxification potential of this renewable biomass was significantly enhanced after modification. Modified biomass could be used as an efficient and low‐cost green‐type material with good application potential for zearalenone detoxification. © 2018 Society of Chemical Industry

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Biological detoxification of zearalenone by Aspergillus niger strain FS10

Cited by 58 publications

References 39 publications

Biodegradation of aflatoxin-B1 and zearalenone by Streptomyces sp. collection

Biodegradation of aflatoxin-B1 and zearalenone by Streptomyces sp. collection

Strategies and Methodologies for Developing Microbial Detoxification Systems to Mitigate Mycotoxins

Biosorptive detoxification of zearalenone biotoxin by surface‐modified renewable biomass: process dynamics and application

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