2015
DOI: 10.1016/j.mrgentox.2015.06.003
|View full text |Cite
|
Sign up to set email alerts
|

Biological effects of in vitro THz radiation exposure in human foetal fibroblasts

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

5
43
1

Year Published

2016
2016
2022
2022

Publication Types

Select...
8

Relationship

1
7

Authors

Journals

citations
Cited by 55 publications
(49 citation statements)
references
References 61 publications
5
43
1
Order By: Relevance
“…Recently, controversial results different from ours were reported [30]. In our study, we could not detect an increase in MN formation following THz exposure, whereas the previous authors indicated that THz exposure (0.1–0.15 THz) induced an increase in the total number of MN and an increase in actin polymerization with no temperature increase of less than 0.2 °C during the exposure.…”
Section: Discussioncontrasting
confidence: 99%
“…Recently, controversial results different from ours were reported [30]. In our study, we could not detect an increase in MN formation following THz exposure, whereas the previous authors indicated that THz exposure (0.1–0.15 THz) induced an increase in the total number of MN and an increase in actin polymerization with no temperature increase of less than 0.2 °C during the exposure.…”
Section: Discussioncontrasting
confidence: 99%
“…According to the literature analysis, THz radiation has no cytotoxic effect while interaction with some types of cells, but causes this effect while interaction with other cells types under similar conditions of exposure. It is noteworthy that a lack of cytotoxic effect happens if covering and supporting tissue cells (epithelial cells [19,33], fibroblasts [20] and keratinocytes [22,23]) are investigated. We suggest that a lack of sensitivity has a function of shielding a body from the THz radiation.…”
Section: Discussionmentioning
confidence: 99%
“…Some studies have demonstrated that this effect does not occur [18][19][20][21][22][23][24][25], whereas in other works the effect was clearly displayed [10][11][12][26][27][28]. Particularly, experiments in papers [19,20,25,28] showed different results after exposure of THz radiation of approximately same frequency (0.10 -0.15 THz) and power density (0.04 -5 mW/cm 2 ). In all mentioned experiments, registration of the effect was carried out using adequate methods; however, the samples under exposure were different.…”
Section: Introductionmentioning
confidence: 99%
“…The occurrence of DNA damage following exposure to 0.1-0.15 THz waves (output power; about 1.5 kW in 4 µs) has been reported [11]. Titova et al reported that exposure to THz pulse at energy of 1.0 and 0.1 µJ for 10 min lead to a DNA damage response in human skin tissue model [35].…”
Section: Discussionmentioning
confidence: 98%
“…The SCENIHR report recommended further research focusing on the impact of THz waves on the skin (low-intensity long-term exposure) and eyes (high-intensity short-term exposure). In recent years, increasing research attention has been focused on the frequency range near 0.1 THz (0.031-5 mW/cm 2 ) [7][8][9][10][11][12][13], which studied genomic instability and damage, genotoxicity, morphological changes, enzyme activity, etc. In addition, a number of studies have focused on the frequency range near 2 THz (0.03 mW/cm 2 -1.4 W/cm 2 ) [14][15][16][17][18][19], which studied gene expression, DNA damages, genotoxicity, inflammatory responses and stress systems etc.…”
Section: Introductionmentioning
confidence: 99%