Biological Effects, Toxicology and Human Safety

Teratogenic and Toxic Effects of Alcohol Ethoxylate and Alcohol Ethoxy Sulfate Surfactants on Xenopus laevis Embryos and Tadpoles

“…O consumption experiments revealed narcotic e!ects, also observed in "sh (Marchetti, 1964) and rat (Bartnik and Kunstler, 1987) and how AE in#uences oxygen consumption. Individuals exposed to AE at stage 46 were used to prevent any reduction due to teratogenic e!ects (reduced branchial exchange surface, altered gill epithelium).…”

“…Anionic detergents deactivate proteins by binding them by polar interaction between the negatively charged hydrophilic group of the surfactant and the positively charged groups of the protein molecule. Nonionic detergents (e.g., Triton X-100) can bind and solubilize lipophilic proteins (Bartnik and Kunstler, 1987).…”