Biological enhancement of graft-tunnel healing in anterior cruciate ligament reconstruction

Saccomanno, Maristella F.; Capasso, Luigi; Fresta, Luca; Milano, Giuseppe

doi:10.11138/jts/2016.4.3.174

Cited by 4 publications

(2 citation statements)

References 76 publications

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“…The hamstring tendon graft is a soft tissue graft that needs to be integrated within the bone tunnels (graft tunnel integration) [ 5 ]. Graft integration is important for the restoration of the native knee kinematics [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Graft tunnel integration occurs early in the tibial tunnel compared with the femoral tunnel after anterior cruciate ligament reconstruction with preserved insertion hamstring tendon graft

Gupta

Singh

Kapoor

et al. 2021

Knee Surg & Relat Res

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Background Preservation of hamstring tendon insertion at the time of anterior cruciate ligament (ACL) reconstruction is a well-known technique; however, its effect on graft integration is not well studied. The present study was conducted to study the graft integration inside the tibial and femoral tunnels, respectively, after ACL reconstruction using hamstring tendon graft with preserved insertion. Methods Twenty-five professional athletes who underwent ACL reconstruction using hamstring tendon graft with preserved tibia insertion were enrolled in the study. Functional outcomes were checked at final follow-up using Lysholm score and Tegner activity scale. Magnetic resonance imaging (MRI) was done at 8 months and 14 months follow-up to study the graft tunnel integration of the ACL graft at both tibial and femoral tunnels. Results The mean Fibrous interzone (FI) score (tibial tunnel) decreased from 2.61 (1–5) at 8 months to 2.04 (1–4) at 14 months follow-up (p = 0.02). The mean FI score (femoral side) decreased from 3.04 (2–5) at 8 months to 2.57 (2–4) at 14 months (p = 0.02). Conclusions Graft integration occurs early in the tibial tunnel as compared with the femur tunnel with preserved insertion hamstring tendon autograft. Trial registration CTRI/2019/07/020320 [registered on 22/07/2019]; http://www.ctri.nic.in/Clinicaltrials/pdf_generate.php?trialid=33884&EncHid=&modid=&compid=%27,%2733884det%27

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Section: Introductionmentioning

confidence: 99%

Graft tunnel integration occurs early in the tibial tunnel compared with the femoral tunnel after anterior cruciate ligament reconstruction with preserved insertion hamstring tendon graft

Gupta

Singh

Kapoor

et al. 2021

Knee Surg & Relat Res

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“…Accordingly, Joints aims to be a journal that focuses on the care of joints generally. In this issue, for example, we bring together articles covering surgery of the hip (1, 2), knee (3), shoulder (4), elbow (5) and ankle (6), as well as replacement surgery (1, 2), arthroscopic surgery (5,7) and open surgery (3,6), and cartilage disease (7,8), regenerative medicine (7,9) and sports traumatology (10). All these are areas of interest that belong to our scientific world, and you find them all here in the same issue-together.…”

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confidence: 99%

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2016

Joints

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Editorial Knee surgery, arthroscopy, sports traumatology, cartilage repair and technology in orthopaedics: looking for a possible unifying concept for joint careThe evolution of orthopaedic surgery over the past thirty years has, in much of the world, been strongly characterized by the concept of minimal invasiveness. This is a phenomenon that, thanks to the spread of arthroscopic techniques, has been particularly marked in the treatment of joint diseases. The knee was the first joint targeted by this revolutionary approach, followed by the shoulder and other large and medium sized joints. Today we are seeing an incredibly rapid increase in arthroscopic treatment of the hip joint. A main advantage of the use of arthroscopy is that it has fostered a better awareness and a greater understanding of joint disease processes, and therefore made it possible to correlate clinical and pathological pictures. This, in turn, has promoted early diagnosis of conditions that can nowadays be treated conservatively, and also through programs designed to prevent evolution of the damage. Second, thanks to arthroscopy, we have been able to develop so-called anatomical surgical repair and reconstruction techniques, designed to restore the joint anatomy to how it was before the onset of the lesion. This seemingly simple concept has had a revolutionary impact; over the years, it has increasingly taken the place of so-called functional surgery -a therapeutic approach whose primary aim was to eliminate the main symptom, even if this meant creating a "new anatomy", which in the long term, however, often proved detrimental to joint, altering its kinematics and allowing progression of the arthritic damage. At the same time, technological and basic scientific research has fostered a growing evolution and application of biotechnologies and regenerative medicine in the repair and reconstruction of connective tissue, primarily joint cartilage. Replacement surgery, too, has kept up with the pace of change, using innovative materials, less and less invasive and more functional prostheses, and sophisticated technologies that are increasing the precision and reproducibility of procedures, and improving the tolerability and survival of implants. A particularly important field of application for cutting-edge regenerative and minimally invasive methods is the care of active young patients, athletes in particular. Sports traumatology is a field that has always needed particularly effective therapeutic approaches, in terms of the speed of healing and the reliability of the result, given that athletes are patients with high functional demands, who are also more exposed to the risk of relapses due to traumatic injury or overuse. Over time, as a result of these developments, the scientific community has been engaged in a sort of ongoing process of aggregation and disaggregation in relation to the above mentioned areas of interest, sometimes creating societies interested in a range of topics (e.g. ESSKA and ISAKOS), and sometimes preferring to create separa...

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Effect of in vivo implantation sites on the graft-to-bone osteointegration induced by gradient nanofibrous scaffolds

Jiang,

Zhang,

Meng

et al. 2023

Applied Materials Today

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Biological enhancement of graft-tunnel healing in anterior cruciate ligament reconstruction

Cited by 4 publications

References 76 publications

Graft tunnel integration occurs early in the tibial tunnel compared with the femoral tunnel after anterior cruciate ligament reconstruction with preserved insertion hamstring tendon graft

Graft tunnel integration occurs early in the tibial tunnel compared with the femoral tunnel after anterior cruciate ligament reconstruction with preserved insertion hamstring tendon graft

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Effect of in vivo implantation sites on the graft-to-bone osteointegration induced by gradient nanofibrous scaffolds

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