Biological evaluation of biphasic calcium phosphate ceramic vertebral laminae

Wang, Jianxin; Chen, Weiqun; Li, Yubao; Fan, Sanjun; Weng, Jie; Zhang, Xingdong

doi:10.1016/s0142-9612(98)00014-3

Cited by 93 publications

(59 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…From the chemical point of view, the vast majority of calcium orthophosphate bioceramics is based on HA, β-TCP, α-TCP and/or biphasic calcium phosphate (BCP, which is an intimate mixture of either β-TCP + HA [118,119,120,121,122,123,124,125,126,127,128,129,130] or α-TCP + HA [7,8,9,10,11]) [131,132,133,134,135,136,137,138,139]. One should note that recently the concept of BCP has been extended by preparation and characterization of biphasic TCP, consisting of α-TCP and β-TCP phases [140,141,142,143,144].…”

Section: Bioceramics Of Calcium Orthophosphatesmentioning

confidence: 99%

Calcium Orthophosphates as Bioceramics: State of the Art

Dorozhkin¹

2010

JFB

216

112

View full text Add to dashboard Cite

In the late 1960s, much interest was raised in regard to biomedical applications of various ceramic materials. A little bit later, such materials were named bioceramics. This review is limited to bioceramics prepared from calcium orthophosphates only, which belong to the categories of bioactive and bioresorbable compounds. There have been a number of important advances in this field during the past 30–40 years. Namely, by structural and compositional control, it became possible to choose whether calcium orthophosphate bioceramics were biologically stable once incorporated within the skeletal structure or whether they were resorbed over time. At the turn of the millennium, a new concept of calcium orthophosphate bioceramics—which is able to promote regeneration of bones—was developed. Presently, calcium orthophosphate bioceramics are available in the form of particulates, blocks, cements, coatings, customized designs for specific applications and as injectable composites in a polymer carrier. Current biomedical applications include artificial replacements for hips, knees, teeth, tendons and ligaments, as well as repair for periodontal disease, maxillofacial reconstruction, augmentation and stabilization of the jawbone, spinal fusion and bone fillers after tumor surgery. Exploratory studies demonstrate potential applications of calcium orthophosphate bioceramics as scaffolds, drug delivery systems, as well as carriers of growth factors, bioactive peptides and/or various types of cells for tissue engineering purposes.

show abstract

Section: Bioceramics Of Calcium Orthophosphatesmentioning

confidence: 99%

Calcium Orthophosphates as Bioceramics: State of the Art

Dorozhkin¹

2010

JFB

216

112

View full text Add to dashboard Cite

show abstract

“…They allow osteogenesis to occur and form tight bonds with host bone tissues [10,11]. Recently, there is a growing interest in developing HA/b-TCP biphasic calcium phosphate (BCP) ceramics as scaffolding materials because they are more effective in bone repair or regeneration than pure HA or pure b-TCP, and have a controllable degradation rate to a certain degree [12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Biphasic calcium phosphate nanocomposite porous scaffolds for load-bearing bone tissue engineering

2004

View full text Add to dashboard Cite

“…From the chemical composition point of view, the vast majority of calcium orthophosphate bioceramics is based on HA, β-TCP, α-TCP and/or biphasic calcium phosphate (BCP). BCP is an intimate mixture of either β-TCP + HA [111][112][113][114][115][116][117][118][119][120][121][122][123][124][125][126] or α-TCP + HA [8][9][10][11][12]) [127][128][129][130][131][132][133][134][135][136]. One should note that recently the concept of BCP has been extended by preparation and characterization of biphasic TCP (BTCP), consisting of both α-TCP and β-TCP phases [137][138][139][140][141].…”

Section: Chemical Composition and Preparationmentioning

confidence: 99%

“…Furthermore, submicron-sized HA powders are biodegraded even faster than the highly porous HA scaffolds. Other examples of bioresorbable materials include porous bioceramic scaffolds made of BCP (which is an intimate mixture of either β-TCP + HA [111][112][113][114][115][116][117][118][119][120][121][122][123][124][125][126] or α-TCP + HA [8][9][10][11][12]) or bone grafts (dense or porous) made of CDHA [152], TCP [411,596,597] and/or ACP [462,598]. One must stress that recently the concepts of bioactive and bioresorbable materials have converged and bioactive materials are made bioresorbable, while bioresorbable materials are made bioactive [599].…”

Section: Interaction With Surrounding Tissues and The Host Responsesmentioning

confidence: 99%

Untitled

2011

BIO

View full text Add to dashboard Cite

In the late 1960's, a strong interest was raised in biomedical applications of ceramic materials (named bioceramics a little bit later). Bioceramics was initially used as reasonable alternatives to metals in order to increase their biocompatibility. However, within a short period, it has grown into a diverse class of biomaterials, presently including three essential types: relatively bioinert, bioactive (or surface reactive) and bioresorbable bioceramics. This review is limited to bioceramics prepared from calcium orthophosphates only, which belong to the categories of bioactive and bioresorbable compounds. There have been a number of important advances in this field during the past 30 -40 years. The research was shifted from an initial study on the develop-ment of bioinert bioceramics towards bioactive and bioresorbable bioceramics, and these different types of calcium orthophosphate bioceramics can be tuned through the structural and compositional control. At the turn of the millennium, a new concept of calcium orthophosphate bioceramics has been developed to promote a regeneration of bones. Current biomedical applications of calcium orthophosphate bioceramics include artificial replacements for hips, knees, teeth, tendons and ligaments, as well as repair for periodontal disease, maxillofacial reconstruction, augmenttation and stabilization of the jawbone, spinal fusion and bone fillers after tumor surgery. Potential future applications of calcium orthophosphate bioceramics are demonstrated in drug delivery systems, effective carriers of growth factors, bioactive peptides and/or various types of cells for tissue engineering purposes.

show abstract

Biological evaluation of biphasic calcium phosphate ceramic vertebral laminae

Cited by 93 publications

References 0 publications

Calcium Orthophosphates as Bioceramics: State of the Art

Calcium Orthophosphates as Bioceramics: State of the Art

Biphasic calcium phosphate nanocomposite porous scaffolds for load-bearing bone tissue engineering

Untitled

Contact Info

Product

Resources

About