2016
DOI: 10.1080/14786419.2016.1269094
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Biological evaluation of phytoconstituents from Polygonum hydropiper

Abstract: Fourteen compounds including vanicoside B (1), vanicoside F (2), vanicoside E (3) and 5,6-dehydrokawain (4), aniba-dimer-A (5), 6,6'-((1α,2α,3β,4β)-2,4-diphenylcyclobutane-1,3-diyl)bis(4-methoxy-2H-pyran-2-one) (6), (+)-ketopinoresinol (7), isorhamnetin (8), 3,7-dihydroxy-5,6-dimethoxy-flavone (9), isalpinin (10), cardamomin (11), pinosylvin (12), 2-desoxy-4-epi-pulchellin (13) and β-sitosterol (14) were isolated from dichloromethane-soluble portion of Polygonum hydropiper. By using Alamar blue assay, compound… Show more

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Cited by 32 publications
(16 citation statements)
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“…Treatment of P. berghei infected mice with 32 mg/kg dose of 350 twice a day for 4 days suppressed parasitaemia by 95% without evidence of toxicity [219]. The phenylpropanoid glycoside vanicoside F ( 351 ), isolated as a major constituent of Polygonum hydropiper (Polygonaceae) aerial parts, also inhibited P. falciparum D6 and W2 strains without cytotoxicity against Vero cells [220].…”
Section: Polyphenolsmentioning
confidence: 99%
“…Treatment of P. berghei infected mice with 32 mg/kg dose of 350 twice a day for 4 days suppressed parasitaemia by 95% without evidence of toxicity [219]. The phenylpropanoid glycoside vanicoside F ( 351 ), isolated as a major constituent of Polygonum hydropiper (Polygonaceae) aerial parts, also inhibited P. falciparum D6 and W2 strains without cytotoxicity against Vero cells [220].…”
Section: Polyphenolsmentioning
confidence: 99%
“…Furthermore, the chemical investigation of the aerial parts of Atraphaxis frutescens resulted in the isolation of five 7-methoxyflavonols [ 20 ]. Isorhamnetin and 3,7-dihydroxy-5,6-dimethoxyflavone were among the compounds isolated from the dichloromethane extract of Polygonum hydropiper [ 24 ], and myricetin 3,7,3′,4′-tetramethyl ether has been isolated from Polygonum viscosum [ 25 ] and Polygonum perfoliatum [ 17 ].…”
Section: Resultsmentioning
confidence: 99%
“…DK has been isolated from several plant species; e.g., the Alpinia speciosa rhizome [36], Alpinia mutica Roxb. [37], Polygonum hydropiper [38], and Alpinia zerumbet [39]. Moreover, DK induces the production of the proangiogenic tumor-derived protein Vascular endothelial growth factor (VEGF) in colorectal cancer cells [37]; exerts anticholinesterase, antioxidant, and neuroprotective effects [40]; and promotes the differentiation of MC3T3-E1 osteoblasts [39].…”
Section: Discussionmentioning
confidence: 99%