Biological evaluation of some novel 1,3-bis substituted-2-isopropylamidines by in silico molecular dynamics and simulation studies

Abstract

A tandem one-pot synthesis of some novel 1,3-bis substitued-2-isopropylamidines has been reported. The overall conversion involves the base mediated tandem acylation of benzylamines with isobutyryl chloride in DCM, and subsequent...