Biological fixation of endosseous implants

Additive Manufacturing Technology Applications Targeting Practical Surgery

“…In the EBM ® process metal structures with well resolved features as small as 0.5-0.2 mm are already quite common. There are other methods allowing surface feature control to smaller scales, down to 10-100 µ, but there are experimental indications that implant surfaces with the micrometer size spatial features in some cases are even more advantageous [7,39,[44][45][46][47][48][49][50] . Controlling the surface features to such high degree of precision in, for example, EBM ® technology is quite challenging due to the process limitations [25] .…”

“…The main aim of such modifications is to improve the growing bone attachment to the metal surface and the strength of the corresponding interface [44,45] . This is achieved through the chemical or electrochemical changes of the metal surface itself, or through depositing the additional layer with higher biocompatibility.…”

The Current Knowledge of Genetic Susceptibility Influencing Dental Implant Outcomes

“…Both aspects (structural and metabolic) are closely related to the features of the mineralized extracellular matrix at implant surfaces. Trabecular bone fills the initial gap and arranges in a three-dimensional network at day 14 (Franchi et al, 2005). The de novo formation of primary bone spongiosa offers not only a biological fixation to ensure secondary implant stability (Ferguson et al, 2006) but also a biological scaffold for cell attachment and bone deposition (Franchi et al, 2005).…”

“…Trabecular bone fills the initial gap and arranges in a three-dimensional network at day 14 (Franchi et al, 2005). The de novo formation of primary bone spongiosa offers not only a biological fixation to ensure secondary implant stability (Ferguson et al, 2006) but also a biological scaffold for cell attachment and bone deposition (Franchi et al, 2005). After 28 days, delineated bone marrow space and thickened bone trabeculae with parallel-fibered and lamellar bone can be found within the interfacial area.…”

Tissue differentiation around a short stemmed metaphyseal loading implant employing a modified mechanoregulatory algorithm: A finite element study

“…Under adequate loading and good stability with minimal micromotion and migration present at the interface, bone should form, gradually replacing granulation tissue and reinforcing the stability at the interface [11][12][13][14] . Excessive micromotion leads to the formation of cartilage and fibrous tissues that present a weak interface and can lead to long term loosening [15][16][17] .…”