2021
DOI: 10.1002/elps.202100124
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Biological nanoparticles: Relevance as novel target drug delivery systems and leading chromatographic isolation approaches

Abstract: Nanotechnology is one of the most promising technologies of the 21st century, and it is now presenting an enormous impact on target drug delivery. In this context, the recent use of natural vesicle‐like nanoparticles such as extracellular vesicles (i.e., exosomes, microvesicles, and apoptotic bodies) and virus‐like particles is rendering encouraging results mostly because these delivery systems present cargo versatility, favorable body circulating advantages, biocompatibility, immunogenicity, and the capacity … Show more

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Cited by 5 publications
(2 citation statements)
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“…Non‐enveloped VLPs can be further categorized as single‐ or multiple‐capsid protein VLPs, as they self‐assemble into particles by incorporating one or more viral components. [ 139 ]…”
Section: Virus‐like Particles (Vlp)mentioning
confidence: 99%
“…Non‐enveloped VLPs can be further categorized as single‐ or multiple‐capsid protein VLPs, as they self‐assemble into particles by incorporating one or more viral components. [ 139 ]…”
Section: Virus‐like Particles (Vlp)mentioning
confidence: 99%
“…As the amount and type of these functional molecules present within or on the surface of EVs vary depending on the disease, they could be used for disease diagnosis, prognosis, and therapeutic targets [ 108 , 109 , 110 , 111 , 112 , 113 , 114 ]. EVs are classified into exosomes, microvesicles, and apoptotic bodies, based on differences in particle size and formation mechanisms [ 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 125 , 126 ]. Since exosomes can be regarded as a natural drug delivery system (DDS) that exists in the living body, they are widely used in drug discovery technologies [ 127 , 128 , 129 , 130 , 131 ].…”
Section: Introductionmentioning
confidence: 99%