2017
DOI: 10.1016/b978-0-12-805324-9.00001-7
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Biological Structures

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Cited by 12 publications
(5 citation statements)
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“…In recognition of this, the ESS, currently under construction in Lund (Sweden), has created a deuteration and macromolecular crystallization platform, known as DEMAX (https://europeanspallationsource.se/ science-support-systems/demax). The aims of this platform are to provide ESS users with access and service-level support not only to biological deuteration but also to chemical deuteration (for the preparation of deuterated small molecules, such as inhibitors) and large crystal growth devices in order to maximize the effectiveness of beamtime on the TOF Laue diffractometer NMX (https://europeanspallationsource.se/instruments/ nmx), which will be one of the first beamlines to come online at the ESS (Fisher et al 2017).…”
Section: Discussionmentioning
confidence: 99%
“…In recognition of this, the ESS, currently under construction in Lund (Sweden), has created a deuteration and macromolecular crystallization platform, known as DEMAX (https://europeanspallationsource.se/ science-support-systems/demax). The aims of this platform are to provide ESS users with access and service-level support not only to biological deuteration but also to chemical deuteration (for the preparation of deuterated small molecules, such as inhibitors) and large crystal growth devices in order to maximize the effectiveness of beamtime on the TOF Laue diffractometer NMX (https://europeanspallationsource.se/instruments/ nmx), which will be one of the first beamlines to come online at the ESS (Fisher et al 2017).…”
Section: Discussionmentioning
confidence: 99%
“…Neutron beams are attenuated based on the chemical composition of nucleus and specimens' geometry [72,74], and they strongly interact with hydrogen nuclei, enabling the observation of water in samples at high spatial resolutions. However, due to the rare availability of neutron beam facilities and expensive resources [73,75], the applicability of the neutron imaging technique is limited.…”
Section: Introductionmentioning
confidence: 99%
“…In the field of soft matter and biophysics, the technique was introduced in the '80s for the study of surfactant thin films but NR, as a technique, remained under exploited for biological relevant samples. In the last two decades, use of NR in the filed of biological sciences increased regularly [1]. This was possible mainly because of improvements in instrumentation, sample environment and modeling approaches.…”
Section: Introductionmentioning
confidence: 99%