Biological tribology properties of the modified polyether ether ketone composite materials

Li, Ning; Chen, Deqiang; Gao, Xiyan; Lu, Lidan; Chen, Weizeng

doi:10.1515/rams-2020-0034

Cited by 13 publications

(6 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One of the promising polymeric materials is polyetheretherketone (PEEK), owing to its excellent mechanical strength, biocompatibility, chemical resistance, and radiolucency. Moreover, PEEK reveals no toxicity to human tissues, shows elastic modulus very close to human bone, and does not interfere with the postoperative X-ray or magnetic resonance imaging (MRI) [ 2 ]. That is why PEEK was already used for the orthopedic implants, such as spinal cages, skull plates, and joints [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Characteristics of Hybrid Bioglass-Chitosan Coatings on the Plasma Activated PEEK Polymer

et al. 2023

View full text Add to dashboard Cite

Polyetheretherketone (PEEK) is a biocompatible, chemically and physically stable radiolucent polymer that exhibits a similar elastic modulus to the normal human bone, making it an attractive orthopedic implant material. However, PEEK is biologically inert, preventing strong enough bonding with the surrounding bone tissue when implanted in vivo. Surface modification and composite preparation are the two main strategies for the improvement of the bioactivity of PEEK. In this study, the plasma activated PEEK surfaces with the embedded bioglass, chitosan, and bioglass-chitosan mixed layers applying from the solution dip-coating technique were investigated. The most prominent factors affecting the coating biocompatibility are strictly connected with the composition of its outer surface (its charge and functional groups), hydrophilic-hydrophobic character, wettability and surface free energy, and topography (size of pores/substructures, roughness, stiffness), as well as the personal characteristics of the patient. The obtained surfaces were examined in terms of wettability and surface-free energy changes. Additionally, FTIR (Fourier Transformation Infrared Spectrometry) and SIMS (Secondary Ion Mass Spectrometry) were applied to establish and control the coating composition. Simultaneously the structure of coatings was visualized with the aid of SEM (Scanning Electron Microscopy). Finally, the obtained systems were incubated in SBF (Simulated Body Fluid) to verify the modifications’ influence on the bioactivity/biocompatibility of the PEEK surface. Different structures with variable compositions, as well as changes of the wettability, were observed depending on the applied modification. In addition, the incubation in SBF suggested that the bioglass-chitosan ratio influenced the formation of apatite-like structures on the modified PEEK surfaces.

show abstract

Section: Introductionmentioning

confidence: 99%

Characteristics of Hybrid Bioglass-Chitosan Coatings on the Plasma Activated PEEK Polymer

et al. 2023

View full text Add to dashboard Cite

show abstract

“…In medical applications, ZrO 2 and SiO 2 are the most popular materials, especially for dental applications, i.e., light-cured composites for restorations and fillers for PMMA for CNC systems [13,14]. Ceramic fillers (CFs) are used to increase the mechanical properties of polymers, i.e., tribological wear resistance and tensile strength, or to decrease absorbability [15,16]. Aluminosilicate cenospheres (CSs) are an alternative for the currently used oxide CFs, which are receiving increasing recognition as a filler for PCCs [17,18].…”

Section: Introductionmentioning

confidence: 99%

Cenospheres-Reinforced PA-12 Composite: Preparation, Physicochemical Properties, and Soaking Tests

et al. 2022

View full text Add to dashboard Cite

The main aim of this research was the preparation of a polymer–ceramic composite with PA-12 as the polymer matrix and modified aluminosilicate cenospheres (CSs) as the ceramic filler. The CSs were subjected to an early purification and cleaning process, which was also taken as a second objective. The CSs were surface modified by a two-step process: (1) etching in Piranha solution and (2) silanization in 3-aminopropyltriethoxysilane. The composite was made for 3D printing by FDM. Raw and modified CSs and a composite with PA-12 were subjected to the following tests: surface development including pores (BET), real density (HP), chemical composition and morphology (SEM/EDS, FTIR), grain analysis (PSD), phase composition (XRD), hardness (HV), and static tensile tests. The composites were subjected to soaking under simulated body fluid (SBF) conditions in artificial saliva for 14, 21, and 29 days. Compared to pure PA-12, PA-12_CS had generally better mechanical properties and was more resistant to SBF at elevated temperatures and soaking times. These results showed this material has potential for use in biomedical applications. These results also showed the necessity of developing a kinetic aging model for aging in different liquids to verify the true value of this material.

show abstract

“…PEEK has long been used as an artificial bone material, and PEEK is not cytotoxic by testing, all of which may indicate the good biocompatibility of PEEK. 46 However, few blood compatibility studies of PEEK-HFMs in oxygenator membranes have been reported. In this study, hemolysis rate and platelet adhesion were applied to evaluate the anticoagulant properties of the unmodified PEEK-HFM and the hydrophilic-modified PEEK-HFMs.…”

Section: Blood Compatibility Evaluationmentioning

confidence: 99%

Improving the Blood Compatibility and the Gas Permeability of Polyether Ether Ketone Hollow Fiber Membrane Used for Membrane Oxygenator via Grafting Hydrophilic Components

Qin

Zhou

Zhang

et al. 2023

ACS Appl. Polym. Mater.

View full text Add to dashboard Cite

As the core component of extracorporeal membrane oxygenation (ECMO) therapy for patients with severe cardiopulmonary failure, the structures and the properties of membrane oxygenator play a crucial role in determining both the efficiency of the gas exchange and the safety of the patients. Herein, with the aim of enhancing the blood compatibility, gas permeability, and durability of the membrane oxygenator, a porous polyether ether ketone hollow fiber membrane (PEEK-HFM) was prepared via a combination of melt spinning and thermally induced phase separation method. Subsequently, three different hydrophilic components including a nonionic polymer (poly(ethylene glycol), PEG), an ionic monomer (acrylic acid, AA), and a zwitterionic monomer (2-methacryloyloxyethyl phosphorylcholine, MPC) were introduced onto the PEEK-HFM surface by UVinduced grafting. The effects of different hydrophilic modifications on the surface characteristics (such as surface water wettability, surface potential, and porous morphologies) and the related properties (including mechanical performance, blood compatibility, and gas exchange permeability) were studied in detail. After grafting different hydrophilic components, not only the pore size of the corresponding PEEK-HFMs decreased compared to the unmodified PEEK-HFMs but also the surface roughness. Meanwhile, although the hydrophilic modifications resulted in the deterioration of the tensile strength of resulting PHFMs, it enhanced the blood compatibility of modified PEEK-HFMs. Moreover, among these modified membranes, the one grafted with MPC showed the best blood compatibility due to its more hydrophilic surface. Additionally, the modified membranes still maintained excellent gas permeability, ensuring the gas exchange performance between carbon dioxide and oxygen. Furthermore, a comprehensive comparison between the modified PEEK-HFMs and a commercial membrane oxygenator (poly(4-methyl-1-pentene), PMP) demonstrated that the modified PEEK-HFMs exhibited higher gas permeability, better blood compatibility, stronger gas exchange ability, and comparable tensile strength, indicating their potential as a high-efficiency option for membrane oxygenators.

show abstract

Biological tribology properties of the modified polyether ether ketone composite materials

Cited by 13 publications

References 37 publications

Characteristics of Hybrid Bioglass-Chitosan Coatings on the Plasma Activated PEEK Polymer

Characteristics of Hybrid Bioglass-Chitosan Coatings on the Plasma Activated PEEK Polymer

Cenospheres-Reinforced PA-12 Composite: Preparation, Physicochemical Properties, and Soaking Tests

Improving the Blood Compatibility and the Gas Permeability of Polyether Ether Ketone Hollow Fiber Membrane Used for Membrane Oxygenator via Grafting Hydrophilic Components

Contact Info

Product

Resources

About