Biologically Active Palladium(II), Zinc(II), and Copper(II) Complexes with Terpene Ligands as Potential Pharmaceutical Drugs

Gur’eva, Ya. A.; Zalevskaya, O. A.; Kuchin, A. V.

doi:10.1134/s1070328423700665

Russ J Coord Chem

2023

DOI: 10.1134/s1070328423700665

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Biologically Active Palladium(II), Zinc(II), and Copper(II) Complexes with Terpene Ligands as Potential Pharmaceutical Drugs

Ya. A. Gur’eva,

O. A. Zalevskaya,

A. V. Kuchin

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2024

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Cited by 2 publications

References 118 publications

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Increasing the Water Solubility of N-Acyl-Substituted Amino Acid Esters as Inhibitors of the Replication of Modern Influenza A Virus Strains In Vitro by Zinc(II) Complexation

Garaev,

Yudin,

Breslav

et al. 2024

Russ. J. Inorg. Chem.

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Increasing the Water Solubility of N-Acyl-Substituted Amino Acid Esters as Inhibitors of the Replication of Modern Influenza A Virus Strains In Vitro by Zinc(II) Complexation

Garaev,

Yudin,

Breslav

et al. 2024

Russ. J. Inorg. Chem.

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Increasing the water solubility of N-acyl-substituted amino acid esters as inhibitors of the replication of modern influenza A virus strains <i>in vitro</i> due to zinc(II) complexation

Garaev,

Yudin,

Breslav

et al. 2024

Žurnal neorganičeskoj himii

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This article proposes carbocyclic derivatives of N-acylated esters of L-amino acids with aromatic carboxylic acids as antiviral low-molecular agents. To increase the water solubility of inhibitors that are insoluble in aqueous solutions, the target compounds were used in the form of zinc(II) complexes. It has been shown that hydrophobic organic compounds in the form of zinc(II)-coordinated ligands are capable of suppressing the replication of an influenza A virus strain resistant to adamantane-type drugs. Zinc(II) chloride at the concentration used does not have antiviral or toxic effects in experiments in vitro.

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Biologically Active Palladium(II), Zinc(II), and Copper(II) Complexes with Terpene Ligands as Potential Pharmaceutical Drugs

Cited by 2 publications

References 118 publications

Increasing the Water Solubility of N-Acyl-Substituted Amino Acid Esters as Inhibitors of the Replication of Modern Influenza A Virus Strains In Vitro by Zinc(II) Complexation

Increasing the Water Solubility of N-Acyl-Substituted Amino Acid Esters as Inhibitors of the Replication of Modern Influenza A Virus Strains In Vitro by Zinc(II) Complexation

Increasing the water solubility of N-acyl-substituted amino acid esters as inhibitors of the replication of modern influenza A virus strains <i>in vitro</i> due to zinc(II) complexation

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