Biologically Derived Nanoarchitectonic Coatings for the Engineering of Hemostatic Needles
Xunhui Zhang,
Hanru Liu,
Huimin Geng
et al.
Abstract:Bleeding after venipuncture could cause blood loss, hematoma,
bruising,
hemorrhagic shock, and even death. Herein, a hemostatic needle with
antibacterial property is developed via coating of biologically derived
carboxymethyl chitosan (CMCS) and Cirsium setosum extract (CsE). The rapid transition from films of the coatings to
hydrogels under a wet environment provides an opportunity to detach
the coatings from needles and subsequently seal the punctured site.
The hydrogels do not significantly influence the he… Show more
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