2021
DOI: 10.1096/fasebj.2021.35.s1.03180
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Biology of the dopamine transporter on human macrophages

Abstract: Neuromodulators, such as norepinephrine and dopamine, regulate immune responses. In addition to receptor competency, select immune cells express machinery to engage in active neurotransmitter transmission. Specifically, macrophages express the norepinephrine (NET) and dopamine transporters (DAT). However, how these transporters ‐ classically studied in central neurons ‐ affect immunity remains poorly understood. To this end, we investigated the expression and function of NET and DAT in human macrophages. We fo… Show more

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