Biomarker analysis of combined oxytetracycline and zinc pollution in earthworms (Eisenia fetida)

Gao, Minling; Qi, Yun; Song, Wei; Zhou, Quan

doi:10.1016/j.chemosphere.2015.06.059

Cited by 30 publications

(9 citation statements)

References 27 publications

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“…Unlike many other environmental pollutants, antibiotics can have a direct biological action on microbes so that they can interfere with the structure and function of the soil microbial community and induce antibiotic resistance genes (ARGs), bringing about a potential genetic pollution risk in different environmental matrices [10e12]. Microorganisms in the environment are more likely to exhibit resistance to antibiotics in the presence of heavy metals and the effects on soil microbial community function are much greater when multiple pollutants are present [13,14]. It has been reported that OTC can significantly reduce soil microbial biomass and alkaline phosphatase activity but increase fungal counts [3,15].…”

Section: Introductionmentioning

confidence: 99%

Effects of different concentrations and application frequencies of oxytetracycline on soil enzyme activities and microbial community diversity

Pan²,

Chen

et al. 2016

European Journal of Soil Biology

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a b s t r a c tAntibiotics in soil can interfere with the structure and function of the soil microbial community and represent a potential genetic pollution risk. The effects of different concentrations and application frequencies of oxytetracycline (OTC) to an agricultural soil on the activities of soil microorganisms and enzymes were investigated during incubation of 120 days. Single once-only high application treatments (1, 3.6, 10, and 30 mg OTC kg À1 soil) and one daily low application treatment (0.03 mg OTC kg À1 soil every day) were compared to simulate OTC application to the soil in sewage sludges or manures or from waste water irrigation. In the single addition treatments, microbial biomass carbon (C mic ) in the soil increased 2.17e3.29 times and 1.37e2.08 times after 7 and 42 d of incubation, respectively, but nitrification potential increased sharply to 3.01e10.9 times after 28 d and dehydrogenase activity was also significantly stimulated after 14 d compared to the zero OTC control and decreased sharply by 120 d. The daily OTC addition treatments promoted C mic (up to 2.64 times) and increased the McIntosh index (p < 0.05) between 60 and 90 days as calculated using Biolog data and compared to the zero OTC control. A single high rate of OTC addition showed a generally more pronounced negative effect on soil microbial community metabolism (but not on functional diversity indices of the soil microbial community) than repeated small rates of addition because with equal amounts of added OTC (single 3.6 mg kg À1 and daily 0.03 mg kg À1 OTC) C mic , nitrification potential and neutral phosphatase activity at 120 d were significantly lower in the single application treatments.

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Section: Introductionmentioning

confidence: 99%

Effects of different concentrations and application frequencies of oxytetracycline on soil enzyme activities and microbial community diversity

Pan²,

Chen

et al. 2016

European Journal of Soil Biology

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“…Pollution of soil in which these animals live and feed may decrease their number that consequently influences the flow of matter and energy through the food webs (Drobne, 1997). Additionally, presence of antibiotic and heavy metals in low concentrations for long periods results metal and antibiotic resistant bacteria (Zhang et al, 2005;De Souza et al, 2006;Park et al, 2009;Gao et al, 2015).…”

Section: Biochemical Analysismentioning

confidence: 99%

Effects of combined treatment of cadmium and oxytetracycline on the terrestrial isopod Porcellio leavis

et al. 2022

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The influence of pharmaceutical residues and heavy metals on living organisms has received global attention. The present study assessed the interactive effect of antibiotic residues and heavy metals in soil, as contaminated food with cadmium (Cd) and oxytetracycline (OTC) on the isopod Porcellio leavis. It was fed on fresh plant leaves contaminated with different concentrations of cadmium, Cd+OTC1000 ppm, Cd+OTC2000 ppm and Cd+OTC3000 ppm for 4 weeks. The changes in the feeding patterns, protein, lipid peroxidation (LPO), catalase activity (CAT), and total free amino acids (TFAA) were recorded. There were significant differences in the obtained results where Cd reduced the egestion ratio (ER) however, OTC enhanced this ratio. Biochemical analysis illustrated that combination between OTC and Cd inhibits the toxic effects of Cd at low concentration (1000 ppm), while at high concentration (3000 ppm) raise the toxicity. Detailed studies are required for further understanding of the interaction between OTC and heavy metals, and also its impact on soil animals and for improving soil risk evaluation.

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“…Pharmaceuticals are released into the environment as a result of medical and veterinary usage (Puckowski et al, 2016). Veterinary medicinal products (VMPs) are widely used to disease treatment, avoid infections, increase weight, or get better feed efficiency and keep the health of terrestrial and aquatic animals (Wang and yates 2008; Gao et al, 2014;Gao et al, 2015;Nica et al, 2015;Li et al, 2015;Jing et al, 2015). Obviously, veterinary pharmaceuticals interact with soil minerals, organic matter, aqueous components, and organisms and are subject to sorption, photo hydrolysis, oxidation, and biodegradation.…”

Section: Introductionmentioning

confidence: 99%

“…(Song, and Guo, 2014). Most veterinary antibiotics cannot be entirely absorbed by animals and are released through feces and urine as the parent compound or as metabolites (Gao et al, 2015). The balance of the soil ecosystem may be destroyed as a result of antibiotic residues and their metabolites in soils.…”

Section: Introductionmentioning

confidence: 99%

Bioaccumulations of Oxytetracycline and Heavy Metal on the Earthworm Aporrectodea Longa

2018

Assiut University Journal of Multidisciplinary Scientific Resea

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Impacts of antibiotic and heavy metals contaminations on agricultural soils attracted world attention. The present study aims to estimate the bioaccumulation of Oxytetracycline (OTC) and selected heavy metals (Fe, Cu, Zn) at Shandwil Island, Sohag, Egypt where they use the manure as an organic fertilizer. Concentrations of OTC, Cu, Fe and Zn in the earth worm (Aporrectodea longa) and the corresponding concentration in litter and soil at 25 locations at the studied site were determined. Some environmental factors (air/soil temperature, soil pH, soil water content and organic matter) were recorded at each investigated location. A. longa showed a significantly higher OTC concentration than litter and soil while studied heavy metals in soil showed higher concentrations than in earthworm and litter. Biomagnification (BMF) and bioconcentration (BCF) factors of OTC were 6.76 and 32.86, respectively. However, BMF and BCF of studied metals were relatively less than OTC and decreased in the following sequence Cu

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Biomarker analysis of combined oxytetracycline and zinc pollution in earthworms (Eisenia fetida)

Cited by 30 publications

References 27 publications

Effects of different concentrations and application frequencies of oxytetracycline on soil enzyme activities and microbial community diversity

Effects of different concentrations and application frequencies of oxytetracycline on soil enzyme activities and microbial community diversity

Effects of combined treatment of cadmium and oxytetracycline on the terrestrial isopod Porcellio leavis

Bioaccumulations of Oxytetracycline and Heavy Metal on the Earthworm Aporrectodea Longa

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