Biomarker responses of the earthworm Aporrectodea tuberculata to copper and zinc exposure: differences between populations with and without earlier metal exposure

Lukkari, Tuomas; Taavitsainen, Mirka; Soimasuo, Markus; Oikari, Aimo; Haimi, Jari

doi:10.1016/j.envpol.2003.12.008

Cited by 110 publications

(44 citation statements)

References 26 publications

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“…The MT levels climbed gradually between the first three environments and then had a large spike in the highest copper environment in short term exposure. The results of both Hansen et al (2006) and Lukkari et al (2004) showed gene expression levels changed above certain copper levels. However, this trend may be restricted by other specific factors including stress duration as long term exposure to copper did not show the same pattern (Lukkari et al 2004).…”

Section: Genetic Correlation Across Environmentsmentioning

confidence: 99%

“…The results of both Hansen et al (2006) and Lukkari et al (2004) showed gene expression levels changed above certain copper levels. However, this trend may be restricted by other specific factors including stress duration as long term exposure to copper did not show the same pattern (Lukkari et al 2004). Possibly, resistance to copper in S. plicata is a threshold trait, where MT gene expression is induced once the copper stress has reached a particular level.…”

Section: Genetic Correlation Across Environmentsmentioning

confidence: 99%

“…The river of highest contamination had significantly higher gene expression of MTs, in comparison with the rivers of medium and low copper contamination. In a manipulative laboratory study, Lukkari et al (2004) exposed earthworms to a control and three copper polluted soils of increasing concentrations. Using protein concentration as a measure of gene expression, they found that as the copper level in the soil increased, MT concentrations also significantly increased.…”

Section: Genetic Correlation Across Environmentsmentioning

confidence: 99%

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Genetic Mechanisms of Pollution Resistance in a Marine Invertebrate

Galletly¹,

Blows²,

Marshall³

2007

Ecological Applications

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Abstract. Pollution is a common stress in the marine environment and one of today's most powerful agents of selection, yet we have little understanding of how anthropogenic toxicants influence mechanisms of adaptation in marine populations. Due to their life history strategies, marine invertebrates are unable to avoid stress and must adapt to variable environments. We examined the genetic basis of pollution resistance across multiple environments using the marine invertebrate, Styela plicata. Gametes were crossed in a quantitative genetic breeding design to enable partitioning of additive genetic variance across a concentration gradient of a common marine pollutant, copper. Hatching success was scored as a measure of stress resistance in copper concentrations of 0, 75, 150, and 350 lg/L. There was a significant genotype 3 environment interaction in hatching success across copper concentrations. Further analysis using factor analytic modeling confirmed a significant dimension of across-environment genetic variation where the genetic basis of resistance to stress in the first three environments differed from that in the environment of highest copper concentration. A second genetic dimension further differentiated between the genetic basis of resistance to low and high stress environments. These results suggest that marine organisms use different genetic mechanisms to adapt to different levels of pollution and that the level of genetic variation to adapt to intense pollution stresses may be limited.

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Section: Genetic Correlation Across Environmentsmentioning

confidence: 99%

Section: Genetic Correlation Across Environmentsmentioning

confidence: 99%

Section: Genetic Correlation Across Environmentsmentioning

confidence: 99%

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Genetic Mechanisms of Pollution Resistance in a Marine Invertebrate

Galletly¹,

Blows²,

Marshall³

2007

Ecological Applications

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“…GSTs neutralise a broad range of xenobiotics and endogenous metabolic by-products via enzymatic glutathione conjugation, glutathione-dependent peroxidase activity or isomerisation reactions (Hayes et al, 2005). Several studies have demonstrated the sensitivity of earthworm GST to metals and pesticide exposure (Aly & Schröder, 2008;Maity et al, 2008;Lukkari et al, 2004;Saint-Denis et al, 2001;Booth et al, 2000). Recently, transcriptome approaches in the earthworm Lumbricus rubellus highlight GSTs as responders to several classes of pollutants including inorganic (cadmium, copper), organic (fluoranthene) and agrochemicals (atrazine) (Bundy et al, 2008;Owen et al, 2008).…”

Section: Biotransformation Enzymesmentioning

confidence: 99%

Earthworm Biomarkers as Tools for Soil Pollution Assessment

Lionetto¹,

Calisi²,

Schettino³

2012

Soil Health and Land Use Management

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“…Some evidences indicate that the induction of the CAT activity is considered valid biomarkers of ambient oxidative pollutants in earthworm toxicology [18][19][20]. GST activity has been used as a potential biomarker of earthworms exposed to heavy metals [21] and pesticides [22] since GST is a detoxification enzyme involved in both the conjugation of glutathione with xenobiotic and antioxidative defenses [23]. However, the response activity of GST and CAT of earthworms exposed to soils with historical DDT contamination are unclear.…”

Section: Introductionmentioning

confidence: 99%

Survival, growth, detoxifying and antioxidative responses of earthworms (Eisenia fetida) exposed to soils with industrial DDT contamination

Shi

Zhang

Huang

et al. 2016

Pesticide Biochemistry and Physiology

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The survival, growth, activity of the biotransformation system phase II enzyme glutathione-S-transferase (GST) and the oxidative defense enzyme catalase (CAT) of earthworms exposed to the contaminated soils from a former DDT plant and reference soils were investigated, and compared with the corresponding indicators in simulated soil-earthworm system, unpolluted natural soils with spiked-in DDT series, to identify the toxic effects of DDT on earthworms and their cellular defense system in complex soil system. The results indicated that DDT level in the contaminated soils was significantly higher than that in the reference soils with similar level of other pollutants and soil characters. The mortality, growth inhibition rates, GST and CST activities of earthworms exposed to the contaminated soils were significantly higher than that in reference soils. The contribution of historical DDT in contaminated soils to earthworms was confirmed by the DDT spiked tests. DDT spiked in soils at rates of higher than 200 mg·kg −1 was significantly toxic to both the survival and the growth of earthworms. DDT significantly stimulated GST and CAT activity in earthworms after 14 days. The CAT and GST activities were also stimulated by DDT exposure at rates of 100 mg·kg −1 after chronic exposure (42 days). The results provide implications for validating the extrapolation from laboratory simulated soils criteria to contaminated soils and for making site risk assessments.

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Biomarker responses of the earthworm Aporrectodea tuberculata to copper and zinc exposure: differences between populations with and without earlier metal exposure

Cited by 110 publications

References 26 publications

Genetic Mechanisms of Pollution Resistance in a Marine Invertebrate

Genetic Mechanisms of Pollution Resistance in a Marine Invertebrate

Earthworm Biomarkers as Tools for Soil Pollution Assessment

Survival, growth, detoxifying and antioxidative responses of earthworms (Eisenia fetida) exposed to soils with industrial DDT contamination

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