Biomarkers in Chronic Kidney Disease - The Linkage Between Inflammation, Ventricular Dysfunction and Overhydration

Ortega, Olimpia

doi:10.5772/23544

Cited by 1 publication

(2 citation statements)

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“…28 In addition, hs-CRP has a long half-life and is independent of other factors. 29 However, our study showed that the hs-CRP level of the subjects had a wide range of variation, which may hinder the analysis between groups. Similar results have also been reported in previous studies that have used CRP as an inflammatory marker in dialysis patients.…”

Section: Discussionmentioning

confidence: 74%

“…The selection of hs‐CRP as a marker of inflammation in our study was due to its strong correlation with cardiovascular prognostic factors . In addition, hs‐CRP has a long half‐life and is independent of other factors . However, our study showed that the hs‐CRP level of the subjects had a wide range of variation, which may hinder the analysis between groups.…”

Section: Discussionmentioning

confidence: 92%

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The effect of intradialytic exercise twice a week on the physical capacity, inflammation, and nutritional status of dialysis patients: A randomized controlled trial

Suhardjono

Umami

Tedjasukmana

et al. 2019

Hemodialysis International

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Introduction: Inactivity, uremia, and malnutrition in dialysis patients may lead to decreased muscle mass and physical capacity. As a preventative measure, dialysis patients are provided with an intradialytic exercise program. Our study aimed to determine the role of intradialytic exercise performed 2 times per week on physical capacity, inflammation, and nutritional status in dialysis patients and to determine which exercises are more suitable for this population. Methods: A randomized clinical trial in which participants were randomly assigned to 1 of 3 groups, i.e., a group of patients performing aerobic exercise, a group of patients performing a combination of aerobic and resistance exercise and the control group. The study was conducted at the Dialysis Unit of Dr. Cipto Mangunkusumo General Hospital, Jakarta for 12 weeks from February to May 2018. The inclusion criteria were dialysis patients aged over 18 years who had undergone routine dialysis for over 3 months. Findings: A total of one hundred twenty patients were included in the study. There was a significant increase in lower extremity strength in the group performing aerobic exercise and in the combined exercise group compared to the lower extremity strength of the control group. There was also a significant increase in the physical component score (PCS) of the KDQOL‐SF™ instrument in the aerobic training and combination exercise groups compared to the PCS of the control group. No significant differences were found between the combination exercise group and the aerobic training group in any outcome. Discussion: Both types of exercise programs significantly increased the lower extremity muscle strength and the PCS of the quality of life index. Combination exercise was not more effective than aerobic exercise for dialysis patients.

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Section: Discussionmentioning

confidence: 74%

Section: Discussionmentioning

confidence: 92%