Biomarkers of Body Composition

Chang, Connie Y.; Lenchik, Leon; Blankemeier, Louis; Chaudhari, Akshay S.; Boutin, Robert D.

doi:10.1055/s-0043-1776430

Semin Musculoskelet Radiol

2024

DOI: 10.1055/s-0043-1776430

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Biomarkers of Body Composition

Connie Y. Chang,

Leon Lenchik,

Louis Blankemeier

et al.

Abstract: The importance and impact of imaging biomarkers has been increasing over the past few decades. We review the relevant clinical and imaging terminology needed to understand the clinical and research applications of body composition. Imaging biomarkers of bone, muscle, and fat tissues obtained with dual-energy X-ray absorptiometry, computed tomography, magnetic resonance imaging, and ultrasonography are described.

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Cited by 1 publication

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Revisiting the beyond BMI paradigm in excess weight diagnosis and management: A call to action

Aguas‐Ayesa,

Yárnoz‐Esquiroz,

Perdomo

et al. 2024

Eur J Clin Investigation

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Adolphe Quételet, a 19th‐century Belgian sociologist and statistician, pioneered the incorporation of statistics into social sciences. He initiated the development of anthropometry since he was interested in identifying the proportions of the ‘ideal man’. He devised a ratio between weight and height, originally termed the Quételet Index, and today widely known and used as the body mass index or BMI. In 1835, he demonstrated that a normal curve accommodates the distribution of human traits articulating his reasoning on human variance around the average. Quételet's long‐lasting legacy of the establishment of a simple measure to classify people's weight relative to an ideal for their height endures today with minor variations having dramatically influenced public health agendas. While being very useful, the limitations of the BMI are well known. Thus, revisiting the beyond BMI paradigm is a necessity in the era of precision medicine with morphofunctional assessment representing the way forward via incorporation of body composition and functionality appraisal. While healthcare systems were originally designed to address acute illnesses, today's demands require a radical rethinking together with an original reappraisal of our diagnosis and treatment approaches from a multidimensional perspective. Embracing new methodologies is the way forward to advance the field, gain a closer look at the underlying pathophysiology of excess weight, keep the spotlight on improving diagnostic performance and demonstrate its clinical validity. In order to provide every patient with the most accurate diagnosis together with the most appropriate management, a high degree of standardization and personalization is needed.

show abstract

Revisiting the beyond BMI paradigm in excess weight diagnosis and management: A call to action

Aguas‐Ayesa,

Yárnoz‐Esquiroz,

Perdomo

et al. 2024

Eur J Clin Investigation

View full text Add to dashboard Cite

show abstract

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Biomarkers of Body Composition

Cited by 1 publication

References 103 publications

Revisiting the beyond BMI paradigm in excess weight diagnosis and management: A call to action

Revisiting the beyond BMI paradigm in excess weight diagnosis and management: A call to action

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