“…The immature inflorescences (capitula or heads) provide the edible part of the plant, and are used fresh, canned or frozen for the preparation of a variety of dishes; its leaves have been exploited as hepatoprotectants, and either choleretic or diuretic agents in traditional medicine since Ancient Roman times. In modern times, leaf extracts have been identified as containing cellular protectants against oxidative damage, HIV integrase inhibitors, and bile-expelling and lipid-lowering agents (Gebhardt 1997(Gebhardt , 1998Kraft 1997;Llorach et al 2002;McDougall et al 1998;Wang et al 2003), whilst roots and seeds have been used to extract inulin (Raccuia and Melilli 2004), with high degree of polymerization, and oil (Maccarone et al 1999;Raccuia and Melilli 2007). The crop is grown across the Middle East, North Africa, South America, China, the USA, and particularly in the Mediterranean region, where it has a significant impact on the rural economy.…”