2022
DOI: 10.4252/wjsc.v14.i12.851
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Biomaterial application strategies to enhance stem cell-based therapy for ischemic stroke

Abstract: BACKGROUND Ischemic stroke is a condition in which an occluded blood vessel interrupts blood flow to the brain and causes irreversible neuronal cell death. Transplantation of regenerative stem cells has been proposed as a novel therapy to restore damaged neural circuitry after ischemic stroke attack. However, limitations such as low cell survival rates after transplantation remain significant challenges to stem cell-based therapy for ischemic stroke in the clinical setting. In order to enhance the… Show more

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