Biomaterials for orthopedic applications and techniques to improve corrosion resistance and mechanical properties for magnesium alloy: a review

Púa, Lizeth Del Carmen Gutiérrez; Montenegro, Juan Carlos Rincón; Reyes, Ana María Fonseca; Rodríguez, Habib Zambrano; Méndez, Virginia Nathaly Paredes

doi:10.1007/s10853-023-08237-5

Cited by 28 publications

(6 citation statements)

References 200 publications

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“…The development of magnesium-based material as supporting material for biodegradable bone implants is one of the current exciting research topics. Since no surgery is required after the implantation, it attracts various researchers [1], [2]. Magnesium has a low density, modulusity close to bone, is biocompatible, and has a high toxic limit, making it attractive for biomaterial implants [1], [3]- [5].…”

Section: Introductionmentioning

confidence: 99%

“…Magnesium has a low density, modulusity close to bone, is biocompatible, and has a high toxic limit, making it attractive for biomaterial implants [1], [3]- [5]. However, to be able to use it, Mg's mechanical properties and degradation rate must be improved [2].…”

Section: Introductionmentioning

confidence: 99%

“…One way to do this is to create a new structure in the form of a composite [2], [5]- [8]. Magnesium composite with bioceramic reinforcements, e.g., calcium phosphate-based such as Hydroxyapatite (HA), is chosen due to its biocompatibility, bioactivity, and approximate chemical composition to bone [1], [3].…”

Section: Introductionmentioning

confidence: 99%

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Composite of Magnesium and Carbonate Apatite for Biodegradable Bone Implants: A Comparative Study on Sintering and Extrusion Techniques

Setyadi,

Suryadi,

Jujur

et al. 2024

Int. J. Adv. Sci. Eng. Inf. Technol.

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Developing biodegradable bone implants using magnesium-based materials has garnered significant attention in research. Magnesium offers favorable properties, such as low density, biocompatibility, elastic modulus like bone, and high toxicity limits. However, improvements are needed in mechanical properties and degradation rate. This study focuses on enhancing these properties by developing a novel composite of magnesium with carbonate apatite (CA) reinforcement, Mg/5CA. Compared to hydroxyapatite (HA), CA offers better absorption and avoids fibrotic tissue formation. However, CA undergoes carbonate decomposition during sintering, leading to composite degradation. To address this, an extrusion process is employed to prevent carbonate decomposition. The advanced sintering and extrusion compaction processes are compared for the Mg/5CA composite, examining density, microstructure, hardness, compressive strength, and biocorrosion. Results demonstrate that extrusion increases relative density while CA slightly reduces it. Microstructural analysis reveals finer and elongated grains, tighter bonding between CA and Mg particles, and reduced microporosity in the extruded composite. Mechanical properties, including hardness distribution and compressive strength, are improved in the extruded composite, and the degradation rate decreases compared to sintering. Overall, the extrusion process effectively enhances Mg/5CA composite properties, positioning it as a promising manufacturing technique for biodegradable implant materials. This research contributes to the development of advanced biodegradable implants, which can have significant applications in the field of medical science. Further investigations in this area can contribute to the ongoing advancements in biodegradable implant technology.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Composite of Magnesium and Carbonate Apatite for Biodegradable Bone Implants: A Comparative Study on Sintering and Extrusion Techniques

Setyadi,

Suryadi,

Jujur

et al. 2024

Int. J. Adv. Sci. Eng. Inf. Technol.

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“…Currently, Mg alloy implants are restricted to nonload bearing positions, and to expand their applicability, it is imperative to improve the mechanical properties of Mg alloys. The mechanical properties and potential medical uses of various biodegradable magnesium alloys, including Mg-Ca based alloys, Mg-Zn based alloys, and Mg-Sr based alloys are reviewed [15]- [17].…”

Section: Introductionmentioning

confidence: 99%

Development of biomechanical behaviour of magnesium alloys for biomedical context

Owida,

Alnaimat,

Al-Naami

et al. 2024

IJEECS

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Magnesium alloys, which belong to the category of biodegradable metals, have a significant amount of potential to be utilized as implant materials, and as a result, they draw a lot of attention. This article is a review that summarizes the mechanical properties of magnesium alloys that are used in medical applications. This article illustrates the mechanical behaviors of magnesium alloys that are used in biomedical applications as well as the ways that may be used to improve the mechanical characteristics of biodegradable magnesium alloys. In conclusion, the difficulties that will need to be overcome in the creation of biodegradable magnesium alloys are discussed.

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“…In view of the benefits as stated above, several extensive reviews have been carried out in the past highlighting the mechanical and biocorrosion attributes of Mg alloys [ 17 , 18 , 19 , 20 , 21 , 22 ]. However, there is still a need for systematic and consolidated reviews on the state of the art, applications, and challenges of Mg-based temporary implants.…”

Section: Introductionmentioning

confidence: 99%

Magnesium-Based Temporary Implants: Potential, Current Status, Applications, and Challenges

Seetharaman

Sankaranarayanan

Gupta

2023

JFB

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Biomedical implants are important devices used for the repair or replacement of damaged or diseased tissues or organs. The success of implantation depends on various factors, such as mechanical properties, biocompatibility, and biodegradability of the materials used. Recently, magnesium (Mg)-based materials have emerged as a promising class of temporary implants due to their remarkable properties, such as strength, biocompatibility, biodegradability, and bioactivity. This review article aims to provide a comprehensive overview of current research works summarizing the above-mentioned properties of Mg-based materials for use as temporary implants. The key findings from in-vitro, in-vivo, and clinical trials are also discussed. Further, the potential applications of Mg-based implants and the applicable fabrication methods are also reviewed.

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Biomaterials for orthopedic applications and techniques to improve corrosion resistance and mechanical properties for magnesium alloy: a review

Cited by 28 publications

References 200 publications

Composite of Magnesium and Carbonate Apatite for Biodegradable Bone Implants: A Comparative Study on Sintering and Extrusion Techniques

Composite of Magnesium and Carbonate Apatite for Biodegradable Bone Implants: A Comparative Study on Sintering and Extrusion Techniques

Development of biomechanical behaviour of magnesium alloys for biomedical context

Magnesium-Based Temporary Implants: Potential, Current Status, Applications, and Challenges

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