Biomechanical analysis of the clinical characteristics of enlarged vestibular aqueduct syndrome with Mondini malformation

Han, Jia-Wei; Wang, Lin; Zhao, Hui; Yang, Shiming

doi:10.1080/00016489.2020.1780312

Cited by 6 publications

(4 citation statements)

References 9 publications

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“…Keeping that in mind, there are many trigger mechanisms that alter inner ear fluid pressure and that in these patients can be associated with the beginning or with the progression of cochlear and vestibular symptoms, such as head trauma, Valsalva maneuver, physical exercise, barotrauma or high fever (25). An higher compliance of the enlarged vestibular aqueduct (just like a higher compliance in Reissner's membrane results in endolymphatic hydrops) (44), causes the vestibular duct to lose its "anti-reflux valve" role in its rugose midpoint as demonstrated by Han et al (45). In particular vestibular dysfunction may be precipitated by the reflux of hyperosmotic fluid into the basal end of the cochlea resulting in an osmotic and chemical imbalance (probably also explaining the worsening course of high frequencies hearing threshold over time in EVA patients).…”

Section: Enlarged Vestibular Aqueductmentioning

confidence: 98%

Vestibular anomalies and dysfunctions in children with inner ear malformations: A narrative review

Brotto

Ariano²,

Sozzi³

et al. 2023

Front. Pediatr.

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About 20% of children with congenital hearing loss present malformations of the inner ear. In the past few years much has been understood about the morphology and function of the anterior part of the labyrinth, since hearing loss may have a dramatic effect on the overall development of a child. Nowadays, for most of them, a chance for hearing rehabilitation is available, making hearing loss a treatable condition. The anomalies range from the lack of development of the whole inner ear to specific anomalies of isolated structures. Despite the frequent concomitant involvement of the posterior part of the labyrinth, this part of the inner ear is frequently neglected while discussing its morphology and dysfunction. Even though vestibular and balance function/dysfunction may have a significant impact on the global development of children, very little is known about these specific disorders in patients with inner ear malformations. The aim of this review is to summarize the available literature about vestibular anomalies and dysfunctions in children with inner ear malformations, discussing what is currently known about the topic.

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Section: Enlarged Vestibular Aqueductmentioning

confidence: 98%

Vestibular anomalies and dysfunctions in children with inner ear malformations: A narrative review

Brotto

Ariano²,

Sozzi³

et al. 2023

Front. Pediatr.

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“…Other projects have been supported for the development of robotic systems related to retinal surgery (48,49), cochlear implants (65), and real-time punctures (53). In addition, separately from programs that supported research on the design and application of surgical robots, the Digital Diagnosis and Treatment Equipment program was established in 2019 to focus on the core components of surgical robots (76, 77).…”

Section: Other Surgical Robotsmentioning

confidence: 99%

Medical Robotics: Opportunities in China

Guo

Chen

Zhao

et al. 2022

Annu. Rev. Control Robot. Auton. Syst.

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Medical robotics is a rapidly advancing discipline that is leading the evolution of robot-assisted surgery, personalized rehabilitation and assistance, and hospital automation. In China, both research and commercial developments in medical robotics have undergone exponential growth in recent years. In this review, we first give an overview of the clinical and social demands that motivate the rapid development in medical robotics. For each subdiscipline (surgery, rehabilitation and personal assistance, and hospital automation), we then summarize the major research projects sponsored by National Key Research and Development Programs. The remaining technical, commercial, and regulatory challenges are highlighted. This review also outlines some of the new opportunities in endoluminal and interventional robotics, micro- and nanorobotics, soft exoskeletons, intelligent human–robot interaction, and telemedicine and telesurgery, which may support the general uptake of robotics in medicine.

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“…Pathological mechanism underling EVA syndrome is related to mutation in the SLC26A4 gene, which encodes for the pendrin protein. However, many other hypotheses have been proposed, including events that cause the variation of cerebrospinal fluid pressure [30]. HRCT is the choice of imaging modality to diagnose EVA [31].…”

Section: Enlarged Vestibular Aqueductmentioning

confidence: 99%

Imaging of inner ear malformations: a primer for radiologists

Feraco

Piccinini²,

Gagliardo

2021

Radiol med

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In the multidisciplinary management of patients with inner ear malformations (IEMs), the correct diagnosis makes the differences in terms of clinical and surgical treatment. The complex anatomical landscape of the inner ear, comprising several small structures, makes imaging of this region particularly challenging for general radiologists. Imaging techniques are important for identifying the presence and defining the type of IEM and the cochlear nerve condition. High-resolution magnetic resonance imaging (MRI) sequences and high-resolution computed tomography (HRCT) are the mainstay imaging techniques in this area. Dedicated MRI and HRCT protocols play an important role in the diagnosis and treatment of patients with inner ear disease. The most suitable technique should be selected depending on the clinical setting. However, in cases of congenital malformation of the inner ear, these techniques should be considered complementary. Since prompt intervention has a positive impact on the treatment outcomes, early diagnosis of IEMs is very important in the management of deaf patients. This article reviews the key concepts of IEMs for clinical radiologists by focusing on recent literature updates, discusses the principal imaging findings and clinical implications for every IEM subgroup, thus providing a practical diagnostic approach.

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Biomechanical analysis of the clinical characteristics of enlarged vestibular aqueduct syndrome with Mondini malformation

Cited by 6 publications

References 9 publications

Vestibular anomalies and dysfunctions in children with inner ear malformations: A narrative review

Vestibular anomalies and dysfunctions in children with inner ear malformations: A narrative review

Medical Robotics: Opportunities in China

Imaging of inner ear malformations: a primer for radiologists

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