Biomechanical and histological evaluation of four different implant macrogeometries in the early osseointegration process: An in vivo animal study

Gehrke, Sérgio Alexandre; Júnior, Jaime Aramburú; Treichel, Tiago Luis Eirles; Dedavid, Berenice Anina

doi:10.1016/j.jmbbm.2021.104935

Cited by 6 publications

(5 citation statements)

References 36 publications

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“…In this regard, Gehrke et al [32] analyzed the effect of four different implant macrogeometries on early bone formation in an animal model. Among the three types of implants studied-cylindrical-conical, tapered, and tapered implants with healing chambers-higher values of ISQ, BIC, and other histological parameters were observed when compared to cylindrical implants.…”

Section: Discussionmentioning

confidence: 99%

Insertion Torque (IT) and Implant Stability Quotient (ISQ) Assessment in Dental Implants with and without Healing Chambers: A Polyurethane In Vitro Study

Mello,

De Carvalho Formiga,

Bianchini

et al. 2023

Applied Sciences

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Primary Stability (PS) depends on different factors, such as bone structure (quality and density), implant characteristics (macro and micro), and the relationship between thread shape and implant insertion hole size. PS is crucial for the prognosis and success of dental implants. The use of healing chambers, which create empty spaces between the implant and peri-implant bone, helps reduce the risk of compressive bone necrosis. High Insertion Torque (IT) values could potentially lead to the deterioration of the implant-abutment connection. However, the optimal implant macro-structure and IT values remain unknown. In this study, implants with healing chambers (Test) and without (Control) were inserted into polyurethane blocks with densities of 10, 20, 30, and 40 pounds per cubic foot (PCF). In blocks with densities of 30 and 40 PCF, Control implants had significantly higher IT values than Test implants. Additionally, Control implants exhibited significantly higher Removal Torque (RT) values than Test implants, but only in the 30 PCF density block (p < 0.0001). However, no differences were found between the implants in the 10, 20, and 40 PCF density blocks. Similarly, no significant differences were observed in the Implant Stability Quotient (ISQ) values between the Test and Control implants. The results of the present study confirm that adding healing chambers to the macro-structure of dental implants can significantly reduce IT values without affecting ISQ values. This suggests the potential for avoiding compression and damage to peri-implant bone while maintaining consistent levels of PS.

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Section: Discussionmentioning

confidence: 99%

Insertion Torque (IT) and Implant Stability Quotient (ISQ) Assessment in Dental Implants with and without Healing Chambers: A Polyurethane In Vitro Study

Mello,

De Carvalho Formiga,

Bianchini

et al. 2023

Applied Sciences

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“…With respect to the Biomed and Osstem implantation systems, the assimilation rate was lower but was also statistically significant. Previous experimental studies (histological [ 17 ] and biochemical [ 18 ] and X-ray analyses [ 19 ]) have also shown how the degree of osseointegration depends on various methods of implantation systems.…”

Section: Discussionmentioning

confidence: 99%

“…Despite the relatively high number of experimental and clinical investigations on this topic (histological [ 17 ], biochemical [ 18 ], and X-ray analyses [ 19 ]), it is currently impossible to make a definite conclusion regarding the kinetics or dynamics of the osseointegration of an implant with the jawbone structure. In our opinion, to remove this blind spot, it is necessary to involve a combination of proven analytical methods to characterize the bone tissue structure after implantation.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the Osseointegration Process of Dental Implants by Electron Paramagnetic Resonance: An In Vivo Study

Kalinnikova¹,

Sadovnikova

Родионов

et al. 2022

Dentistry Journal

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This research work presents an analysis of the process of an implant’s osseointegration to the jawbone tissue. The purpose of this work was to describe the processes of assimilation and the biochemical dynamics which occur during dental implantation using implants with different macro-microstructure surfaces at the level of stable free radicals using the electron paramagnetic resonance (EPR) method. The experimental investigation was conducted on seven Vietnamese minipigs over twelve months old and weighing up to 30 kg using implants with various macro-microstructure surfaces (SLA, RBM, and HSTTM) and implantation systems, namely the Adin, Sunran, Biomed, and Osstem systems. The integration of the implant into the bone triggered biochemical processes with the formation of stable free radicals. The EPR method was used to identify the formed paramagnetic species and to study the dynamics of the interaction between the surface of the implant and the bone after one and two months. The concentration of carbonate surface centers increased with the time that the implant was connected to the hard tissue. The “Sunran” and “HSTTM” were established as the most suitable implantation system and surface type, respectively, thanks to the highest rate of osseointegration (assimilation) with the bone (hard) tissue. Thus, the EPR method provides the opportunity to study implantation processes.

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“…The animals received anesthetic procedures and pre- and postoperative medication following protocols used in previous studies by our research group. 1,2 First, an incision was made to the bone level and a total flap was opened, exposing the dorsal calvarium bone. In each animal, two bone defects were created (right and left sides of the midline) in the posterior (dorsal) portion of the skull, in which the total bone thickness was removed using a 6.5 mm external diameter trephine (Hager & Meisinger GmbH, Neuss, Germany), under intense irrigation with saline solution at room temperature (23 ± 2ºC).…”

Section: Methodsmentioning

confidence: 99%

“…Due to their predictability, dental implants have become a safe alternative for the rehabilitation of missing teeth; despite their success rate being quite high, micro-, and macrogeometric alterations are continually proposed. [1][2][3] However, for the installation of these implants, it is essential that there is adequate bone structure, which is normally affected after tooth loss, as the alveolar bone loses a large part of its volume during the healing process. To recover the bone volume needed for implant placement, regenerative bone grafts are often used.…”

Section: Introductionmentioning

confidence: 99%

Comparative evaluation of two collagen-based biomaterials with different compositions used for bone graft: An experimental animal study

Gehrke

Júnior²,

Treichel

et al. 2022

Journal of Applied Biomaterials & Functional Materials

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A large number of materials with different compositions and shapes have been proposed and studied for the purpose of bone tissue regeneration. Collagen-based materials have shown promising results for this application, with improved physicochemical properties. The aim of the present in vivo animal study was to evaluate and compare two commercially available collagen-based biomaterials for bone regeneration, with these being implanted in circumferential bone defects created in the calvarium of rabbits. Twenty rabbits received bilateral parietal osteotomies, performed with the aid of a 6.5 mm diameter trephine. Two groups were created: the BC group, where the defect was filled with a scaffold composed of 90% bovine bone particles and 10% porcine collagen, and the EG group, where the defect was filled with a scaffold composed of 75% hydroxyapatite particles of bovine origin and 25% bovine collagen. Ten animals were sacrificed at 30 days and another 10 at 45 days after implantation, and the samples were processed and histologically analyzed. In the evaluations of the samples at 30 days, no important differences were found in the results. However, in the samples at 45 days after surgery, the EG group showed better results than the BC group samples, mainly in terms of the amount of bone matrix formation ( P < 0.0001) and the volume in area measured in each sample, where the EG group had a value 65% higher than that in the BC group samples. Based on the results obtained, we conclude that the amount of collagen and the particle characteristics present in the composition of the scaffolds can directly influence the amount of neoformation and/or bone regeneration.

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Biomechanical and histological evaluation of four different implant macrogeometries in the early osseointegration process: An in vivo animal study

Cited by 6 publications

References 36 publications

Insertion Torque (IT) and Implant Stability Quotient (ISQ) Assessment in Dental Implants with and without Healing Chambers: A Polyurethane In Vitro Study

Insertion Torque (IT) and Implant Stability Quotient (ISQ) Assessment in Dental Implants with and without Healing Chambers: A Polyurethane In Vitro Study

Analysis of the Osseointegration Process of Dental Implants by Electron Paramagnetic Resonance: An In Vivo Study

Comparative evaluation of two collagen-based biomaterials with different compositions used for bone graft: An experimental animal study

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