Biomechanical Properties of the Periaortic Abdominal Tissue: It is Not as Fragile as It Seems.

Gomes, Vivian Carla; Silva, Luiz Fernando Ferraz da; Silvestre, Gina Camillo; Queiroz, Alexandre; Marques, Michele Alberto; Zyngier, Szulim Ber; Silva, Erasmo Simão da

doi:10.1016/j.avsg.2020.11.028

Cited by 3 publications

(1 citation statement)

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“…The fact that one reader was not blinded to smoking status may have introduced a possible bias, but it was shown that excellent inter-rater agreement was achieved with the blinded reader. Second, THE estimates effective aortic stiffness only, which reflects elastic properties of the vessel wall and surrounding tissue and in part the prevailing arterial blood pressure at the time of measurement 29 – 31 . Additionally, with current technology THE does not allow determination of SWS throughout the cardiac cycle because the traveling pulse wave causes deflection of the aortic wall during systole precluding determination of systolic SWS within the vessel wall.…”

Section: Discussionmentioning

confidence: 99%

The effect of smoking on quantification of aortic stiffness by ultrasound time-harmonic elastography

Elgeti

Fröhlich

Wismayer

et al. 2022

Sci Rep

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Smoking is a significant cardiovascular risk factor that causes stiffening of the central arteries, especially the aorta. While vessel stiffness can be determined indirectly by measuring pulse wave velocity, elastography allows image-based determination of vessel stiffness while at the same time providing information on vascular morphology. This study compares abdominal aortic wall stiffness as measured by ultrasound time-harmonic elastography (THE) in fifteen smokers and fifteen age-matched non-smoking controls without a history of cardiovascular disease. Smokers had a significantly higher abdominal aortic wall stiffness with a mean shear wave speed of 2.66 m/s (95% confidence interval (CI) 2.59–2.72 m/s) compared to 2.40 m/s (95% CI 2.34–2.47 m/s) (p < 0.01) in the group of non-smokers. All other baseline characteristics including aortic diameter showed no significant differences. Inter-rater variability was excellent with an intraclass correlation coefficient of 0.99 (95% CI 0.98–0.99). Our results show that THE is sensitive to subclinical stiffening of the aorta in young and middle-aged smokers even before morphological changes occur and may therefore has the potential to serve as a screening tool for early aortic abnormalities and longitudinal risk factors for cardiovascular health.

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Section: Discussionmentioning

confidence: 99%