Biomechanics of Transcatheter Aortic Valve Implant

Abstract

Transcatheter aortic valve implantation (TAVI) has grown exponentially within the cardiology and cardiac surgical spheres. It has now become a routine approach for treating aortic stenosis. Several concerns have been raised about TAVI in comparison to conventional surgical aortic valve replacement (SAVR). The primary concerns regard the longevity of the valves. Several factors have been identified which may predict poor outcomes following TAVI. To this end, the lesser-used finite element analysis (FEA) was used to quantify the properties of calcifications which affect TAVI valves. This method can also be used in conjunction with other integrated software to ascertain the functionality of these valves. Other imaging modalities such as multi-detector row computed tomography (MDCT) are now widely available, which can accurately size aortic valve annuli. This may help reduce the incidence of paravalvular leaks and regurgitation which may necessitate further intervention. Structural valve degeneration (SVD) remains a key factor, with varying results from current studies. The true incidence of SVD in TAVI compared to SAVR remains unclear due to the lack of long-term data. It is now widely accepted that both are part of the armamentarium and are not mutually exclusive. Decision making in terms of appropriate interventions should be undertaken via shared decision making involving heart teams.

Fluid–Structure Interaction Aortic Valve Surgery Simulation: A Review

“…Since 2002, when the TAVI procedure was first introduced, a variety of prostheses, different in their design parameters, have been developed; the biological materials of the leaflets, methods of their processing, shapes and materials of prosthesis frameworks, etc. were changed [101,102]. Transcatheter implantation is a novel alternative method for correcting aortic stenosis in patients considered inoperable or at high risk of traditional aortic valve replacement [103][104][105].…”